RF Pulse Concatenation for Spatially Selective Inversion

Klaas P. Pruessmann, Xavier Golay, Matthias Stuber, Markus B. Scheidegger, Peter Boesiger

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


It is shown that spatially selective inversion and saturation can be achieved by concatenation of RF pulses with lower flip angles. A concatenation rule which enables global doubling of the flip angle of any given excitation pulse applied to initial z magnetization is proposed. In this fashion, the selectivity of the single pulse is preserved, making the high selectivity achievable in the low flip-angle regime available for inversion and large flip-angle saturation purposes. The profile quality achievable with exemplary concatenated pulses is investigated in comparison with adiabatic inversion. It is verified that by using concatenated inversion in the transfer insensitive labeling technique (TILT), the MT artifact is suppressed.

Original languageEnglish (US)
Pages (from-to)58-65
Number of pages8
JournalJournal of Magnetic Resonance
Issue number1
StatePublished - Sep 2000


  • Magnetization transfer
  • RF pulses
  • Selective inversion
  • Spin labeling
  • TILT

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Nuclear and High Energy Physics
  • Condensed Matter Physics


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