Reye syndrome associated with vaccination with live virus vaccines. An exploration of possible etiologic relationships

D. M. Morens, N. A. Halsey, L. B. Schonberger, J. V. Baublis

Research output: Contribution to journalArticle

Abstract

To determine whether vaccination with live virus vaccines may be etiologically related to Reye syndrome, the authors examined 404 cases reported to the Center for Disease Control. Fifteen of 269 children with Reye syndrome had been inoculated with live virus vaccines within 30 days before onset of illness. Although this temporal relationship may have occurred by chance, seasonal distribution and clustering of incubation periods suggests that live virus vaccines may occasionally serve as cofactors in the etiology of Reye syndrome through undefined mechanisms.

Original languageEnglish (US)
Pages (from-to)42-44
Number of pages3
JournalClinical pediatrics
Volume18
Issue number1
DOIs
StatePublished - Jan 1 1979
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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