@article{1a08c4fcc90d4a4ea22146c829ab726c,
title = "Revisiting and refining roles of neural guidance cues in circuit assembly",
abstract = "Neural guidance mechanisms ensure the precise targeting and synaptogenesis events essential for normal circuit function. Neuronal growth cones encounter numerous attractive and repulsive cues as they navigate toward their intermediate and final targets; temporal and spatial regulation of these responses are critical for circuit assembly. Recent work highlights the complexity of these events throughout neural development and the multifaceted functions of a wide range of guidance cues. Here, we discuss recent studies that leverage advances in genetics, single cell tracing, transcriptomics and proteomics to further our understanding of the molecular mechanisms underlying neural guidance and overall circuit organization.",
author = "Dorskind, {Joelle M.} and Kolodkin, {Alex L.}",
note = "Funding Information: We thank Greg Bashaw, Roman Giger, Zhuhao Wu, an anonymous reviewer, and members of the Kolodkin laboratory for helpful comments and critical reading of the manuscript. Work in the authors{\textquoteright} laboratory is supported by funding from the NIH to A.L.K., and by funding to J.M.D. from the Cellular and Molecular Medicine graduate training program NIH/GM T32 Training Grant at The Johns Hopkins School of Medicine. Funding Information: We thank Greg Bashaw, Roman Giger, Zhuhao Wu, an anonymous reviewer, and members of the Kolodkin laboratory for helpful comments and critical reading of the manuscript. Work in the authors? laboratory is supported by funding from the NIH to A.L.K. and by funding to J.M.D. from the Cellular and Molecular Medicine graduate training program NIH/GM T32 Training Grant at The Johns Hopkins School of Medicine. Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",
year = "2021",
month = feb,
doi = "10.1016/j.conb.2020.07.005",
language = "English (US)",
volume = "66",
pages = "10--21",
journal = "Current Opinion in Neurobiology",
issn = "0959-4388",
publisher = "Elsevier Limited",
}