Review the application and mechanism of action of ribavirin in therapy of hepatitis C

Emmanuel Thomas, Marc G. Ghany, T. Jake Liang

Research output: Contribution to journalArticle

Abstract

Ribavirin has been used as an antiviral agent for several decades. Although it has activity against numerous viruses, its major use clinically has been in the treatment of respiratory syncytial virus in paediatric patients and chronic HCV infection in both children and adults. This review highlights the clinical application and mechanism of action of ribavirin and discusses the future role of ribavirin in treatment of HCV where there are intense research efforts to improve therapy.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalAntiviral Chemistry and Chemotherapy
Volume23
Issue number1
DOIs
StatePublished - 2012
Externally publishedYes

ASJC Scopus subject areas

  • Virology
  • Drug Discovery
  • Pharmacology
  • Medicine(all)

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