Review of dynamic contrast-enhanced MRI: Technical aspects and applications in the musculoskeletal system

Parvinder Sujlana, Jan Skrok, Laura M Fayad

Research output: Contribution to journalArticlepeer-review

Abstract

Although postcontrast imaging has been used for many years in musculoskeletal imaging, dynamic contrast enhanced (DCE) MRI is not routinely used in many centers around the world. Unlike conventional contrast-enhanced sequences, DCE-MRI allows the evaluation of the temporal pattern of enhancement in the musculoskeletal system, perhaps best known for its use in oncologic applications (such as differentiating benign from malignant tumors, evaluating for treatment response after neoadjuvant chemotherapy, and differentiating postsurgical changes from residual tumor). However, DCE-MRI can also be used to evaluate inflammatory processes such as Charcot foot and synovitis, and evaluate bone perfusion in entities like Legg Calve Perthes disease and arthritis. Finally, vascular abnormalities and associated complications may be better characterized with DCE-MRI than conventional imaging. The goal of this article is to review the applications and technical aspects of DCE-MRI in the musculoskeletal system.

Original languageEnglish (US)
JournalJournal of Magnetic Resonance Imaging
DOIs
StateAccepted/In press - 2017
Externally publishedYes

Keywords

  • Dynamic contrast enhancement
  • MRI
  • Synovitis
  • Tumor
  • Vascular

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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