Review of critical care and emergency approaches to stroke

The human evidence seems to suggest that edema occurs and progressively worsens with ICH. There may be a relationship between the production of relative amounts of edema and the size of hematoma. This relationship could be important to predicting functional outcome. Further direct and prospective evaluation of this hypothesis in animal models and further evaluation of the natural history of edema production in response to human hematoma volume may help to refine an appropriate target for treatment.