Reversible monocular cataract simulating Amaurosis fugax

R. P. Paylor, J. B. Selhorst, Robert S Weinberg

Research output: Contribution to journalArticle

Abstract

In a patient having brittle, juvenile-onset diabetes, transient monocular visual loss occurred repeatedly whenever there were wide fluctuations in serum glucose. Amaurosis fungax was suspected. The visual loss differed, however, in that it persisted over a period of hours to several days. Direct observation eventually revealed that the relatively sudden change in vision of one eye was associated with opacification of the lens and was not accompanied by an afferent pupillary defect. Presumably, a hyperosmotic gradient had developed with the accumulation of glucose and sorbitol within the lens. Water was drawn inward, altering the composition of the lens fibers and thereby lowering the refractive index, forming a reversible cataract. Hypoglycemia is also hypothesized to have played a role in the formation of a higher osmotic gradient. The unilaterality of the cataract is attributed to variation in the permeability of asymmetric posterior subcapsular cataracts.

Original languageEnglish (US)
Pages (from-to)423-425
Number of pages3
JournalAnnals of Ophthalmology
Volume17
Issue number7
StatePublished - 1985
Externally publishedYes

Fingerprint

Amaurosis Fugax
Cataract
Lenses
Pupil Disorders
Glucose
Refractometry
Sorbitol
Blindness
Type 1 Diabetes Mellitus
Hypoglycemia
Permeability
Observation
Water
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Reversible monocular cataract simulating Amaurosis fugax. / Paylor, R. P.; Selhorst, J. B.; Weinberg, Robert S.

In: Annals of Ophthalmology, Vol. 17, No. 7, 1985, p. 423-425.

Research output: Contribution to journalArticle

Paylor, RP, Selhorst, JB & Weinberg, RS 1985, 'Reversible monocular cataract simulating Amaurosis fugax', Annals of Ophthalmology, vol. 17, no. 7, pp. 423-425.
Paylor, R. P. ; Selhorst, J. B. ; Weinberg, Robert S. / Reversible monocular cataract simulating Amaurosis fugax. In: Annals of Ophthalmology. 1985 ; Vol. 17, No. 7. pp. 423-425.
@article{ac1c29cd5eba495cb944a54fb83383a2,
title = "Reversible monocular cataract simulating Amaurosis fugax",
abstract = "In a patient having brittle, juvenile-onset diabetes, transient monocular visual loss occurred repeatedly whenever there were wide fluctuations in serum glucose. Amaurosis fungax was suspected. The visual loss differed, however, in that it persisted over a period of hours to several days. Direct observation eventually revealed that the relatively sudden change in vision of one eye was associated with opacification of the lens and was not accompanied by an afferent pupillary defect. Presumably, a hyperosmotic gradient had developed with the accumulation of glucose and sorbitol within the lens. Water was drawn inward, altering the composition of the lens fibers and thereby lowering the refractive index, forming a reversible cataract. Hypoglycemia is also hypothesized to have played a role in the formation of a higher osmotic gradient. The unilaterality of the cataract is attributed to variation in the permeability of asymmetric posterior subcapsular cataracts.",
author = "Paylor, {R. P.} and Selhorst, {J. B.} and Weinberg, {Robert S}",
year = "1985",
language = "English (US)",
volume = "17",
pages = "423--425",
journal = "Annals of Ophthalmology",
issn = "0003-4886",
publisher = "Humana Press",
number = "7",

}

TY - JOUR

T1 - Reversible monocular cataract simulating Amaurosis fugax

AU - Paylor, R. P.

AU - Selhorst, J. B.

AU - Weinberg, Robert S

PY - 1985

Y1 - 1985

N2 - In a patient having brittle, juvenile-onset diabetes, transient monocular visual loss occurred repeatedly whenever there were wide fluctuations in serum glucose. Amaurosis fungax was suspected. The visual loss differed, however, in that it persisted over a period of hours to several days. Direct observation eventually revealed that the relatively sudden change in vision of one eye was associated with opacification of the lens and was not accompanied by an afferent pupillary defect. Presumably, a hyperosmotic gradient had developed with the accumulation of glucose and sorbitol within the lens. Water was drawn inward, altering the composition of the lens fibers and thereby lowering the refractive index, forming a reversible cataract. Hypoglycemia is also hypothesized to have played a role in the formation of a higher osmotic gradient. The unilaterality of the cataract is attributed to variation in the permeability of asymmetric posterior subcapsular cataracts.

AB - In a patient having brittle, juvenile-onset diabetes, transient monocular visual loss occurred repeatedly whenever there were wide fluctuations in serum glucose. Amaurosis fungax was suspected. The visual loss differed, however, in that it persisted over a period of hours to several days. Direct observation eventually revealed that the relatively sudden change in vision of one eye was associated with opacification of the lens and was not accompanied by an afferent pupillary defect. Presumably, a hyperosmotic gradient had developed with the accumulation of glucose and sorbitol within the lens. Water was drawn inward, altering the composition of the lens fibers and thereby lowering the refractive index, forming a reversible cataract. Hypoglycemia is also hypothesized to have played a role in the formation of a higher osmotic gradient. The unilaterality of the cataract is attributed to variation in the permeability of asymmetric posterior subcapsular cataracts.

UR - http://www.scopus.com/inward/record.url?scp=0022385138&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022385138&partnerID=8YFLogxK

M3 - Article

C2 - 4037603

AN - SCOPUS:0022385138

VL - 17

SP - 423

EP - 425

JO - Annals of Ophthalmology

JF - Annals of Ophthalmology

SN - 0003-4886

IS - 7

ER -