Reversible leukoencephalopathy associated with cerebral amyloid angiopathy

U. Oh, R. Gupta, J. W. Krakauer, A. G. Khandji, S. S. Chin, Mitchell S.V. Elkind

Research output: Contribution to journalArticlepeer-review

Abstract

The authors describe three patients with reversible leukoencephalopathy associated with cerebral amyloid angiopathy (CAA). Rapid progression of neurologic symptoms was followed by dramatic clinical and radiographic improvement. Pathologically, CAA was associated with varying degrees of inflammation ranging from none to transmural granulomatous infiltration. In the appropriate clinical context, the MRI finding of lobar white matter edema with evidence of prior hemosiderin deposition may indicate the presence of a reversible CAA leukoencephalopathy.

Original languageEnglish (US)
Pages (from-to)494-497
Number of pages4
JournalNeurology
Volume62
Issue number3
DOIs
StatePublished - Feb 10 2004
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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