Return of secondary findings in genomic sequencing: Military implications

Lydia D. Hellwig; Clesson Turner; Teri A. Manolio; Mark Haigney; Cynthia A. James; Brittney Murray; Dale F. Szpisjak; Sheila Muldoon; Juvianee Estrada-Veras; Alyson Krokosky; Mauricio J. De Castro

doi:10.1002/mgg3.483

Return of secondary findings in genomic sequencing: Military implications

Lydia D. Hellwig, Clesson Turner, Teri A. Manolio, Mark Haigney, Cynthia A. James, Brittney Murray, Dale F. Szpisjak, Sheila Muldoon, Juvianee Estrada-Veras, Alyson Krokosky, Mauricio J. De Castro

School of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Background: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems. Methods: In this paper, we consider potential military-specific implications of returning genomic sequencing secondary findings to ensure the proper protections, policies, and processes are in place for the use of this information. Results: We specifically use two examples to highlight potential military implications of the return of secondary findings. Conclusion: Clinicians and researchers are strongly encouraged to consider the military implications of the return of results for informed consent of service members or their families undergoing clinical or research genomic sequencing.

Original language	English (US)
Article number	e00483
Journal	Molecular Genetics and Genomic Medicine
Volume	7
Issue number	2
DOIs	https://doi.org/10.1002/mgg3.483
State	Published - Feb 2019

Keywords

genomics
military
secondary findings

ASJC Scopus subject areas

Molecular Biology
Genetics
Genetics(clinical)

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10.1002/mgg3.483

Cite this

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title = "Return of secondary findings in genomic sequencing: Military implications",

abstract = "Background: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems. Methods: In this paper, we consider potential military-specific implications of returning genomic sequencing secondary findings to ensure the proper protections, policies, and processes are in place for the use of this information. Results: We specifically use two examples to highlight potential military implications of the return of secondary findings. Conclusion: Clinicians and researchers are strongly encouraged to consider the military implications of the return of results for informed consent of service members or their families undergoing clinical or research genomic sequencing.",

keywords = "genomics, military, secondary findings",

author = "Hellwig, {Lydia D.} and Clesson Turner and Manolio, {Teri A.} and Mark Haigney and James, {Cynthia A.} and Brittney Murray and Szpisjak, {Dale F.} and Sheila Muldoon and Juvianee Estrada-Veras and Alyson Krokosky and {De Castro}, {Mauricio J.}",

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year = "2019",

month = feb,

doi = "10.1002/mgg3.483",

language = "English (US)",

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journal = "Molecular Genetics and Genomic Medicine",

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T1 - Return of secondary findings in genomic sequencing

T2 - Military implications

AU - Hellwig, Lydia D.

AU - Turner, Clesson

AU - Manolio, Teri A.

AU - Haigney, Mark

AU - James, Cynthia A.

AU - Murray, Brittney

AU - Szpisjak, Dale F.

AU - Muldoon, Sheila

AU - Estrada-Veras, Juvianee

AU - Krokosky, Alyson

AU - De Castro, Mauricio J.

PY - 2019/2

Y1 - 2019/2

N2 - Background: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems. Methods: In this paper, we consider potential military-specific implications of returning genomic sequencing secondary findings to ensure the proper protections, policies, and processes are in place for the use of this information. Results: We specifically use two examples to highlight potential military implications of the return of secondary findings. Conclusion: Clinicians and researchers are strongly encouraged to consider the military implications of the return of results for informed consent of service members or their families undergoing clinical or research genomic sequencing.

AB - Background: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems. Methods: In this paper, we consider potential military-specific implications of returning genomic sequencing secondary findings to ensure the proper protections, policies, and processes are in place for the use of this information. Results: We specifically use two examples to highlight potential military implications of the return of secondary findings. Conclusion: Clinicians and researchers are strongly encouraged to consider the military implications of the return of results for informed consent of service members or their families undergoing clinical or research genomic sequencing.

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Return of secondary findings in genomic sequencing: Military implications

Abstract

Keywords

ASJC Scopus subject areas

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