Retrospective serosurvey for human granulocytic ehrlichiosis agent in urban white-footed mice from Maryland

Joseph E. Bunnell; J. Stephen Dumler; James E. Childs; Gregory E. Glass

doi:10.7589/0090-3558-34.1.179

Retrospective serosurvey for human granulocytic ehrlichiosis agent in urban white-footed mice from Maryland

Joseph E. Bunnell, J. Stephen Dumler, James E. Childs, Gregory E. Glass

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

Archived serum samples from 111 Peromyscus leucopus, collected 1984-88 in Baltimore City (Maryland, USA), were analyzed by indirect immunofluorescence assay. Sera from two (2%) individuals contained antibodies reactive to Ehrlichia equi and the human granulocytic ehrlichiosis (HGE) agent. This suggests that the HGE agent or an antigenically related organism has been present in rodent populations in this locality for more than a decade, and was present in the region at least 12 yr before a case of human disease was recognized.

Original language	English (US)
Pages (from-to)	179-181
Number of pages	3
Journal	Journal of wildlife diseases
Volume	34
Issue number	1
DOIs	https://doi.org/10.7589/0090-3558-34.1.179
State	Published - Jan 1998
Externally published	Yes

Keywords

Ehrlichia equi
Human granulocytic ehrlichiosis
Indirect immunofluorescence assay
Peromyscus leucopus
Reservoir
White-footed mouse

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Ecology

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10.7589/0090-3558-34.1.179

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title = "Retrospective serosurvey for human granulocytic ehrlichiosis agent in urban white-footed mice from Maryland",

abstract = "Archived serum samples from 111 Peromyscus leucopus, collected 1984-88 in Baltimore City (Maryland, USA), were analyzed by indirect immunofluorescence assay. Sera from two (2%) individuals contained antibodies reactive to Ehrlichia equi and the human granulocytic ehrlichiosis (HGE) agent. This suggests that the HGE agent or an antigenically related organism has been present in rodent populations in this locality for more than a decade, and was present in the region at least 12 yr before a case of human disease was recognized.",

keywords = "Ehrlichia equi, Human granulocytic ehrlichiosis, Indirect immunofluorescence assay, Peromyscus leucopus, Reservoir, White-footed mouse",

author = "Bunnell, {Joseph E.} and Dumler, {J. Stephen} and Childs, {James E.} and Glass, {Gregory E.}",

year = "1998",

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doi = "10.7589/0090-3558-34.1.179",

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T1 - Retrospective serosurvey for human granulocytic ehrlichiosis agent in urban white-footed mice from Maryland

AU - Bunnell, Joseph E.

AU - Dumler, J. Stephen

AU - Childs, James E.

AU - Glass, Gregory E.

PY - 1998/1

Y1 - 1998/1

N2 - Archived serum samples from 111 Peromyscus leucopus, collected 1984-88 in Baltimore City (Maryland, USA), were analyzed by indirect immunofluorescence assay. Sera from two (2%) individuals contained antibodies reactive to Ehrlichia equi and the human granulocytic ehrlichiosis (HGE) agent. This suggests that the HGE agent or an antigenically related organism has been present in rodent populations in this locality for more than a decade, and was present in the region at least 12 yr before a case of human disease was recognized.

AB - Archived serum samples from 111 Peromyscus leucopus, collected 1984-88 in Baltimore City (Maryland, USA), were analyzed by indirect immunofluorescence assay. Sera from two (2%) individuals contained antibodies reactive to Ehrlichia equi and the human granulocytic ehrlichiosis (HGE) agent. This suggests that the HGE agent or an antigenically related organism has been present in rodent populations in this locality for more than a decade, and was present in the region at least 12 yr before a case of human disease was recognized.

KW - Ehrlichia equi

KW - Human granulocytic ehrlichiosis

KW - Indirect immunofluorescence assay

KW - Peromyscus leucopus

KW - Reservoir

KW - White-footed mouse

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Retrospective serosurvey for human granulocytic ehrlichiosis agent in urban white-footed mice from Maryland

Abstract

Keywords

ASJC Scopus subject areas

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