Retrospective analysis of birth weight and prostate cancer in the health professionals follow-up study

Elizabith A. Platz, Edward Giovannucci, Eric B. Rimm, Gary C. Curhan, Donna Spiegelman, Graham A. Colditz, Walter C. Willet

Research output: Contribution to journalArticlepeer-review

Abstract

The authors retrospectively evaluated the relation between birth weight and prostate cancer (1986-1994) among 21,140 men of the Health Professionals Follow-up Study who reported in 1994 their weight at birth. No relation between birth weight and prostate cancer (n = 545) was observed in multivariate logistic models. For high stage/grade tumors (n = 213), compared with birth weights <7.0 lbs (<3,175 g), the relative risks were 1.20 (95% confidence interval (CI) 0.79-1.83) for 8.5-9.9 lbs (3,855.6-4,490.6 g) and 1.30 (95% CI 0.80-2.10) for ≤10 lbs (≤4,536 g). These findings do not support an overall association between birth weight and prostate cancer incidence, but the possibility of a modest positive association between birth weight and high stage/grade prostatic cancer cannot be excluded.

Original languageEnglish (US)
Pages (from-to)1140-1144
Number of pages5
JournalAmerican journal of epidemiology
Volume147
Issue number12
DOIs
StatePublished - Jun 15 1998

Keywords

  • Birth weight
  • Cohort studies
  • Prostatic neoplasms

ASJC Scopus subject areas

  • Epidemiology

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