An adult male baboon with long-term femoral catheter placement 'was examined because of a two-day history of recumbency and apparent difficulty defecating and urinating. Physical examination revealed a large mass located in the caudoventral region of the abdomen. Relevant hematologic and serum biochemical abnormalities included hypochromic anemia, neutropenia, lymphocytosis, hypoproteinemia, hypoalbuminemia, and bilirubinemia. Urine analysis revealed bilirubinuria, proteinuria, and hematuria. Fine needle aspiration of the mass along with plain and contrast radiography confirmed presence of a large retroperitoneal hematoma. We hypothesize that the pathogenesis of the lesion in this baboon was erosion of the indwelling femoral catheter thorough the vessel wall with subsequent retroperitoneal accumulation of hemorrhage, fluids, and test compounds.
|Original language||English (US)|
|Number of pages||3|
|Journal||Contemporary Topics in Laboratory Animal Science|
|State||Published - Dec 1 1997|
ASJC Scopus subject areas
- Animal Science and Zoology