Retrograde Control of Neural Circuit Formation

Christopher D. Deppmann, David D. Ginty

Research output: Contribution to journalArticlepeer-review

Abstract

Glial-derived neurotrophic factor (GDNF), secreted by skeletal muscle, triggers expression of the ETS transcription factor Pea3 in a subset of motor neurons in the spinal cord. In this issue, Vrieseling and Arber (2006) find that this retrograde GDNF-Pea3 signal controls dendrite patterning and assembly of a sensory-motor reflex circuit.

Original languageEnglish (US)
Pages (from-to)1306-1307
Number of pages2
JournalCell
Volume127
Issue number7
DOIs
StatePublished - Dec 29 2006

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

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