TY - JOUR
T1 - Retinochoroidal morphology described by wide-field montage imaging of spectral domain optical coherence tomography
AU - Mori, Keisuke
AU - Kanno, Junji
AU - Gehlbach, Peter L.
N1 - Funding Information:
Supported in part by NIH, RO1 EY021540 to 01A1, Research to Prevent Blindness, The J. Willard and Alice S. Marriott Foundation, The Gale Trust, The Ehler’s Family Foundation; generous gifts from Mr. Bill Wilbur, and Paul and Mary Ellen Keck (P.L.G.); and a grant-in-aid for scientific research (24592641) from the Ministry of Education, Culture and Science in Japan (K.M.).
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Purpose: To present baseline images of the vitreous, retina, and choroid from the macula to the periphery in normal patients using a novel montaging technique of spectral domain optical coherence tomography. Methods: Twenty-six normal eyes of 22 healthy volunteers were enrolled in this study. Montaged images of four radial optical coherence tomography scans through the fovea were obtained from each subject. Results: In the macula, there were six identifiable retinal layers as well as four bands in the outer retina. In the periphery, the ganglion cell layer was not identifiable. The external limiting membrane, the second band, and the retinal pigment epithelium were continuously delineated from the macula to the periphery. The third band was not visible in the periphery. Conclusion: Spectral domain optical coherence tomography montaged images provide wide-angle images of the vitreous, retina, and choroid, allowing for evaluation of peripheral findings and examination of relationships between peripheral and posterior disease. The maximum scan length achieved here was 36 mm. The scan length is approximately three times than that provided by conventional posterior scanning and is consistent with known dimensions of the eye. This method is achievable with current commercially available devices and may contribute to decision making in clinical practice.
AB - Purpose: To present baseline images of the vitreous, retina, and choroid from the macula to the periphery in normal patients using a novel montaging technique of spectral domain optical coherence tomography. Methods: Twenty-six normal eyes of 22 healthy volunteers were enrolled in this study. Montaged images of four radial optical coherence tomography scans through the fovea were obtained from each subject. Results: In the macula, there were six identifiable retinal layers as well as four bands in the outer retina. In the periphery, the ganglion cell layer was not identifiable. The external limiting membrane, the second band, and the retinal pigment epithelium were continuously delineated from the macula to the periphery. The third band was not visible in the periphery. Conclusion: Spectral domain optical coherence tomography montaged images provide wide-angle images of the vitreous, retina, and choroid, allowing for evaluation of peripheral findings and examination of relationships between peripheral and posterior disease. The maximum scan length achieved here was 36 mm. The scan length is approximately three times than that provided by conventional posterior scanning and is consistent with known dimensions of the eye. This method is achievable with current commercially available devices and may contribute to decision making in clinical practice.
KW - montaged images
KW - normal retinochoroidal structure
KW - spectral domain optical coherence tomography
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U2 - 10.1097/IAE.0000000000000703
DO - 10.1097/IAE.0000000000000703
M3 - Article
C2 - 26241154
AN - SCOPUS:84957609964
SN - 0275-004X
VL - 36
SP - 375
EP - 384
JO - Retina
JF - Retina
IS - 2
ER -