Abstract
Several immunohistochemical and biochemical characteristics of retinas from two patients with retinitis pigmentosa (RP) were examined. Histochemically, interphotoreceptor retinoid-binding protein (IRBP) was found in the interphotoreceptor space in small areas of preserved peripheral retina, although enzyme-linked immunosorbent assay suggested that little IRBP was present. Antibodies to glial fibrillary acidic protein and factor VIII-related antigen corroborated retinal gliosis and retinal vessel attenuation, respectively, in the RP cases. Fibronectin showed similar staining in normal and affected tissue.
Original language | English (US) |
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Pages (from-to) | 79-83 |
Number of pages | 5 |
Journal | Canadian Journal of Ophthalmology |
Volume | 21 |
Issue number | 3 |
State | Published - Jan 1 1986 |
Externally published | Yes |
ASJC Scopus subject areas
- Ophthalmology