Abstract
Several immunohistochemical and biochemical characteristics of retinas from two patients with retinitis pigmentosa (RP) were examined. Histochemically, interphotoreceptor retinoid-binding protein (IRBP) was found in the interphotoreceptor space in small areas of preserved peripheral retina, although enzyme-linked immunosorbent assay suggested that little IRBP was present. Antibodies to glial fibrillary acidic protein and factor VIII-related antigen corroborated retinal gliosis and retinal vessel attenuation, respectively, in the RP cases. Fibronectin showed similar staining in normal and affected tissue.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 79-83 |
| Number of pages | 5 |
| Journal | Canadian Journal of Ophthalmology |
| Volume | 21 |
| Issue number | 3 |
| State | Published - Jan 1 1986 |
| Externally published | Yes |
ASJC Scopus subject areas
- Ophthalmology