Déchirures de l’épithélium pigmentaire rétinien

Translated title of the contribution: Retinal pigment epithelial tears

M. Sastre-Ibáñez, C. Martínez-Rubio, R. Molina-Pallete, P. Martínez- López-Corell, L. Wu, J. F. Arévalo, R. Gallego-Pinazo

Research output: Contribution to journalReview articlepeer-review

Abstract

A retinal pigment epithelial (RPE) tear is a well-known complication of retinal pigment epithelial detachments (PED) and may cause a significant visual impairment. The most common cause is a vascularized PED in patients with exudative age-related macular degeneration (AMD). The development of diagnostic imaging techniques brings us closer to the etiology and pathophysiological mechanisms of this entity, offering us new strategies for treatment and follow-up. The advent of intravitreal antiangiogenic treatment (anti-VEGF) has led to an increase in the number of reported cases of RPE tears, which are an important vision-limiting factor during treatment. However, RPE tears may occur spontaneously or as a consequence of thermal laser treatment, photodynamic therapy or anti-VEGF therapy. It is accepted that the mechanism of RPE tears is multifactorial. The optimization of the functional outcome of this complication has been described with continuous treatment with antiangiogenic drugs. The goal of the present review is to evaluate the incidence, risk factors and treatment of RPE tears.

Translated title of the contributionRetinal pigment epithelial tears
Original languageFrench
Pages (from-to)63-72
Number of pages10
JournalJournal Francais d'Ophtalmologie
Volume42
Issue number1
DOIs
StatePublished - Jan 2019

Keywords

  • Age-related macular degeneration
  • Anti-angiogenics
  • Retinal pigment epithelial (RPE) tear
  • Retinal pigment epithelial detachments
  • Risk factors for retinal pigment epithelial tear

ASJC Scopus subject areas

  • Ophthalmology

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