Retinal findings in membranoproliferative glomerulonephritis

Ahmad M. Mansour, Luiz H. Lima, J. Fernando Arevalo, Miguel Hage Amaro, Virginia Lozano, Alaa Bou Ghannam, Errol W. Chan

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed for a period of 1.5–37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes) had diffuse thickening of Bruch's membrane, and two patients (3 eyes) had detachment of the retinal pigment epithelium with serous retinal detachment. Drusen tended to widen over a period of 10-year follow-up in one case. Conclusions and importance: Drusen remain the ocular stigmata for MPGN occuring at an early age. The retinal disease is progressive with gradual thickening of Bruch's membrane and occurrence of retinal pigment epithelium detachment.

Original languageEnglish (US)
Pages (from-to)83-90
Number of pages8
JournalAmerican Journal of Ophthalmology Case Reports
StatePublished - Sep 2017


  • Drusen
  • Macular degeneration
  • Membranoproliferative glomerulonephritis
  • Retinal pigment epithelial detachment

ASJC Scopus subject areas

  • Ophthalmology


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