Retinal findings in membranoproliferative glomerulonephritis

Ahmad M. Mansour, Luiz H. Lima, J Fernando Arevalo, Miguel Hage Amaro, Virginia Lozano, Alaa Bou Ghannam, Errol W. Chan

Research output: Contribution to journalArticle

Abstract

Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed for a period of 1.5–37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes) had diffuse thickening of Bruch's membrane, and two patients (3 eyes) had detachment of the retinal pigment epithelium with serous retinal detachment. Drusen tended to widen over a period of 10-year follow-up in one case. Conclusions and importance: Drusen remain the ocular stigmata for MPGN occuring at an early age. The retinal disease is progressive with gradual thickening of Bruch's membrane and occurrence of retinal pigment epithelium detachment.

Original languageEnglish (US)
Pages (from-to)83-90
Number of pages8
JournalAmerican Journal of Ophthalmology Case Reports
Volume7
DOIs
StatePublished - Sep 1 2017

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Membranoproliferative Glomerulonephritis
Bruch Membrane
Retinal Pigment Epithelium
Christianity
Retinal Diseases
Fluorescein Angiography
Optical Coherence Tomography
Retinal Detachment

Keywords

  • Drusen
  • Macular degeneration
  • Membranoproliferative glomerulonephritis
  • Retinal pigment epithelial detachment

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Retinal findings in membranoproliferative glomerulonephritis. / Mansour, Ahmad M.; Lima, Luiz H.; Arevalo, J Fernando; Amaro, Miguel Hage; Lozano, Virginia; Ghannam, Alaa Bou; Chan, Errol W.

In: American Journal of Ophthalmology Case Reports, Vol. 7, 01.09.2017, p. 83-90.

Research output: Contribution to journalArticle

Mansour, Ahmad M. ; Lima, Luiz H. ; Arevalo, J Fernando ; Amaro, Miguel Hage ; Lozano, Virginia ; Ghannam, Alaa Bou ; Chan, Errol W. / Retinal findings in membranoproliferative glomerulonephritis. In: American Journal of Ophthalmology Case Reports. 2017 ; Vol. 7. pp. 83-90.
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AU - Ghannam, Alaa Bou

AU - Chan, Errol W.

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