TY - JOUR
T1 - Retinal disease in marfan syndrome
T2 - From the marfan eye consortium of Chicago
AU - Rahmani, Safa
AU - Lyon, Alice T.
AU - Fawzi, Amani A.
AU - Maumenee, Irene H.
AU - Mets, Marilyn B.
PY - 2015/10
Y1 - 2015/10
N2 - Background and Objective: To study the prevalence of peripheral retinal disease in patients with Marfan Syndrome (MFS). Patients and Methods: In this observational, cross-sectional case series, patients with MFS were recruited by the Marfan Eye Consortium of Chicago during the National Marfan Foundation's annual conference. Patients underwent a fully dilated exam by vitreoretinal specialists in addition to ultra- widefield fundus photography using a scanning laser ophthalmoscope (Optos 200Tx; Optos PLC, Dunfermline, Scotland, United Kingdom). Results: Clinical examination revealed posterior segment pathology in 18% of eyes with increased incidence to 70% in patients with a subluxed lens. In six out of 10 subjects in whom the clinical exam was suboptimal (young age, small pupil, and limited cooperation), the Optos provided a superior view of the peripheral retina compared to clinical exam alone. Conclusion: Clinical exam of MFS patients revealed similar posterior segment pathology as noted in previous literature, with improved detection of peripheral retinal disease with the use of ultra-widefield imaging.
AB - Background and Objective: To study the prevalence of peripheral retinal disease in patients with Marfan Syndrome (MFS). Patients and Methods: In this observational, cross-sectional case series, patients with MFS were recruited by the Marfan Eye Consortium of Chicago during the National Marfan Foundation's annual conference. Patients underwent a fully dilated exam by vitreoretinal specialists in addition to ultra- widefield fundus photography using a scanning laser ophthalmoscope (Optos 200Tx; Optos PLC, Dunfermline, Scotland, United Kingdom). Results: Clinical examination revealed posterior segment pathology in 18% of eyes with increased incidence to 70% in patients with a subluxed lens. In six out of 10 subjects in whom the clinical exam was suboptimal (young age, small pupil, and limited cooperation), the Optos provided a superior view of the peripheral retina compared to clinical exam alone. Conclusion: Clinical exam of MFS patients revealed similar posterior segment pathology as noted in previous literature, with improved detection of peripheral retinal disease with the use of ultra-widefield imaging.
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U2 - 10.3928/23258160-20151008-06
DO - 10.3928/23258160-20151008-06
M3 - Article
C2 - 26469233
AN - SCOPUS:84944532970
SN - 2325-8160
VL - 46
SP - 936
EP - 941
JO - Ophthalmic Surgery Lasers and Imaging Retina
JF - Ophthalmic Surgery Lasers and Imaging Retina
IS - 9
ER -