Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes

Badr O. Alahmadi, Sulaiman M. Alsulaiman, J Fernando Arevalo

Research output: Contribution to journalArticle

Abstract

Purpose. To determine the functional and anatomic outcomes of rhegmatogenous retinal detachment (RRD) surgery in patients with Down syndrome. Methods. A retrospective chart review was performed of patients with Down syndrome who had undergone surgery for RRD at King Khalid Eye Specialist Hospital between 1995 and 2014. Results. A total of 245 patients with Down syndrome were evaluated during the study period. Eighteen eyes of 15 patients (6.1%) with RRD were identified. Three out of 15 patients (20%) presented with bilateral retinal detachment. All eyes presented with macula off retinal detachment. The retina was successfully reattached in 16/18 (88.8%) eyes after a mean follow-up of 48 months. The final postoperative visual acuity ranged from light perception to 20/125 (median: hand motion) (11/18 eyes). Conclusions. The anatomic success rate of retinal reattachment surgery in patients with Down syndrome is comparable to the general population. Patients with Down syndrome should undergo regular ophthalmic examinations for early diagnosis. Despite late diagnosis and the presence of proliferative vitreoretinopathy (PVR) in some patients, favorable anatomical outcomes can be achieved.

Original languageEnglish (US)
Article number6971591
JournalJournal of Ophthalmology
Volume2016
DOIs
StatePublished - 2016

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Retinal Detachment
Down Syndrome
Proliferative Vitreoretinopathy
Delayed Diagnosis
Visual Acuity
Retina
Early Diagnosis
Hand
Light
Population

ASJC Scopus subject areas

  • Ophthalmology

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Retinal Detachment in Down Syndrome : Characteristics and Surgical Outcomes. / Alahmadi, Badr O.; Alsulaiman, Sulaiman M.; Arevalo, J Fernando.

In: Journal of Ophthalmology, Vol. 2016, 6971591, 2016.

Research output: Contribution to journalArticle

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N2 - Purpose. To determine the functional and anatomic outcomes of rhegmatogenous retinal detachment (RRD) surgery in patients with Down syndrome. Methods. A retrospective chart review was performed of patients with Down syndrome who had undergone surgery for RRD at King Khalid Eye Specialist Hospital between 1995 and 2014. Results. A total of 245 patients with Down syndrome were evaluated during the study period. Eighteen eyes of 15 patients (6.1%) with RRD were identified. Three out of 15 patients (20%) presented with bilateral retinal detachment. All eyes presented with macula off retinal detachment. The retina was successfully reattached in 16/18 (88.8%) eyes after a mean follow-up of 48 months. The final postoperative visual acuity ranged from light perception to 20/125 (median: hand motion) (11/18 eyes). Conclusions. The anatomic success rate of retinal reattachment surgery in patients with Down syndrome is comparable to the general population. Patients with Down syndrome should undergo regular ophthalmic examinations for early diagnosis. Despite late diagnosis and the presence of proliferative vitreoretinopathy (PVR) in some patients, favorable anatomical outcomes can be achieved.

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