Results of Indocyanine Green Videoangiography (ICGV) guided treatment of "hot spots" in eyes with Serous Pigment Epithelial Detachment (S-PED) from Age-Related Macular Degeneration (ARMD)

P. R. Gagnon, R. P. Murphy, J. T. Thompson, C. J. Hiner

Research output: Contribution to journalArticle

Abstract

Purpose. To evaluate the outcome of eyes with neovascular S-PED from ARMD presenting with different ICGV patterns of "hot spots". Methods. We determined the visual acuity (VA) outcome and ICGV patterns of 8 eyes (8 patients) treated with laser photocoagulation and followed from 0.7 to 2.25 years (mean 1.4 years). Four of 8 eyes presented initially with "hot spots" located under the dome of the S-PED (3 round/oval shape, 1 well-defined plaque) and 4 were located at the margin of the S-PED (3 linear, 1 tightly clustered). The "hot spot" was <1/4 DA (disc area) in size (small) for 6 of 8 eyes and >1/4 DA <1DA (large) for 2 of 8 eyes. Results. Five of 8 eyes showed stable/improved VA (within 2 Snellen lines) at a mean of 1.4 years. Two of 8 eyes had moderate decrease in VA (3 to 5 Snellen lines) at a mean of 1.5 years. One of 8 eyes had severe VA loss (6 Snellen lines) at 1.3 years. Four of 8 eyes required additional laser due to new areas of leakage including both with large "hot spots". In the group without recurrent leakage, 3 had stable/improved VA and 1 had moderate VA loss. In the group developing recurrent leakage, 2 had stable/improved VA; 1 developed moderate and 1 developed severe visual loss. Concision. 63% of the eyes were improved or stable at a mean of 1.4 years with only 1 eye developing severe visual loss. A randomized clinical trial is needed to determine if laser photocoagulation of "hot spots" on ICGV improves the prognosis on the natural history.

Original languageEnglish (US)
Pages (from-to)S116
JournalInvestigative Ophthalmology and Visual Science
Volume37
Issue number3
StatePublished - Feb 15 1996

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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