Restoring blood pressure reperfused Wernicke's area and improved language

Argye E. Hillis; P. B. Barker; N. J. Beauchamp; B. D. Winters; M. Mirski; R. J. Wityk

doi:10.1212/WNL.56.5.670

Restoring blood pressure reperfused Wernicke's area and improved language

Argye E. Hillis, P. B. Barker, N. J. Beauchamp, B. D. Winters, M. Mirski, R. J. Wityk

School of Medicine

Research output: Contribution to journal › Article › peer-review

79 Scopus citations

Abstract

Longitudinal clinical and imaging data from a patient who sustained a left frontal-temporal stroke with hypoperfusion of the adjacent Wernicke's area are reported. His language deficits were partially ameliorated by pharmacologically increasing his blood pressure, and were exacerbated when blood pressure dropped. There was a striking temporal and statistical correlation between mean arterial pressure and language accuracy. MR perfusion imaging showed that language gains were accompanied by improved perfusion of Wernicke's area when mean arterial pressure was increased.

Original language	English (US)
Pages (from-to)	670-672
Number of pages	3
Journal	Neurology
Volume	56
Issue number	5
DOIs	https://doi.org/10.1212/WNL.56.5.670
State	Published - Mar 13 2001

ASJC Scopus subject areas

Clinical Neurology

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AU - Hillis, Argye E.

AU - Barker, P. B.

AU - Beauchamp, N. J.

AU - Winters, B. D.

AU - Mirski, M.

AU - Wityk, R. J.

PY - 2001/3/13

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AB - Longitudinal clinical and imaging data from a patient who sustained a left frontal-temporal stroke with hypoperfusion of the adjacent Wernicke's area are reported. His language deficits were partially ameliorated by pharmacologically increasing his blood pressure, and were exacerbated when blood pressure dropped. There was a striking temporal and statistical correlation between mean arterial pressure and language accuracy. MR perfusion imaging showed that language gains were accompanied by improved perfusion of Wernicke's area when mean arterial pressure was increased.

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Restoring blood pressure reperfused Wernicke's area and improved language

Abstract

ASJC Scopus subject areas

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