Restoration of transforming growth factor-β receptor II expression in colon cancer cells with microsatellite instability increases metastatic potential in vivo

Medicine & Life Sciences

• Microsatellite Instability 100%
• Growth Factor Receptors 95%
• Transforming Growth Factors 85%
• Colonic Neoplasms 73%
• Phosphatidylinositol 3-Kinases 48%
• Cell Movement 40%
• Colorectal Neoplasms 25%
• Cell Survival 24%
• Neoplasm Metastasis 20%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 19%
• Microsatellite Repeats 17%
• Cadherins 16%
• Intercellular Signaling Peptides and Proteins 13%
• Survival Rate 12%
• Down-Regulation 11%
• Apoptosis 9%
• Mutation 9%
• Survival 9%
• Liver 8%
• Incidence 7%
• In Vitro Techniques 7%
• Therapeutics 2%

Chemical Compounds

• Effector 88%
• Cell Viability 80%
• LY294002 74%
• Growth Factor 47%
• Apoptotic 46%
• Mutation 34%
• Resistance 25%