Abstract
To evaluate the reestablishment of the bronchial circulation in lung transplantation, the authors studied 10 immunosuppressed dogs up to 14 weeks after left lung allografting. Selective in vivo bronchial arteriograms were performed repetitively via the transfemoral route. In the early postoperative period, no filling of vessels distal to the bronchial anastomosis could be shown. After 12 days, however, continuity of the bronchial arteries across the anastomosis was present, and dye filled ramifications of these vessels were visualized on the secondary and tertiary bronchi. Reconstitution of the bronchial circulation was also confirmed by postmortem studies after injecting the isolated descending thoracic aorta with colored radiopaque material (microfil). The bronchial mucosa at autopsy was examined microscopically. There was no correlation between its viability and bronchial artery regeneration. Although early ischemia of the transplant bronchus may be a factor in the bronchial complications that follow lung transplantation, the present study indicates that this ischemia is not due to failure of bronchial artery regeneration.
Original language | English (US) |
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Pages (from-to) | 792-795 |
Number of pages | 4 |
Journal | Journal of Thoracic and Cardiovascular Surgery |
Volume | 73 |
Issue number | 5 |
DOIs | |
State | Published - 1977 |
Externally published | Yes |
ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine