Restless legs syndrome: Nonpharmacologic and pharmacologic treatments

John W. Winkelman, Richard P. Allen, Penny Tenzer, Wayne Hening

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Treatment of restless legs syndrome (RLS) has as its goals alleviation of the primary symptoms of the disorder and establishment of normal sleep. Dopamine agonists are considered first-line treatment when daily treatment for primary RLS is indicated. Gabapentin and opioids may be of value for refractory cases. Initial treatment of secondary RLS should address the underlying cause.

Original languageEnglish (US)
Pages (from-to)13-16
Number of pages4
Issue number10
StatePublished - Oct 1 2007
Externally publishedYes


  • Anticonvulsants
  • Dopamine agonists
  • Iron supplementation
  • Opioids
  • Restless legs syndrome
  • Sedatives
  • Sleep deprivation

ASJC Scopus subject areas

  • Geriatrics and Gerontology


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