Restless legs syndrome is associated with DSM-IV major depressive disorder and panic disorder in the community

Hochang Benjamin Lee, Wayne A. Hening, Richard P. Allen, Amanda E. Kalaydjian, Christopher J. Earley, William W. Eaton, Constantine G. Lyketsos

Research output: Contribution to journalArticlepeer-review

142 Scopus citations

Abstract

The authors examined the association between restless legs syndrome (RLS) and DSM-IV major depressive disorder and panic disorder based on Wave III and IV of the Baltimore ECA follow-up study. Of 1071 participants, 1024 completed the RLS Questionnaire and Diagnostic Interview Schedule. Adjusted odds ratio for diagnosis of major depressive disorder (4.7, 95% confidence interval [1.6, 14.5]) and panic disorder (12.9 [3.6, 46.0]) and comorbidity of major depressive disorder and panic disorder (9.7 [1.4, 69.0]) in the past 12 months suggested a strong association between restless legs syndrome and major depressive disorder andlor panic disorder.

Original languageEnglish (US)
Pages (from-to)101-105
Number of pages5
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume20
Issue number1
DOIs
StatePublished - 2008

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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