Restless legs syndrome in a community sample of Korean adults: Prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders

Seong Jin Cho, Jin Pyo Hong, Bong Jin Hahm, Hong Jin Jeon, Sung Man Chang, Maeng Je Cho, Hochang B. Lee

Research output: Contribution to journalArticle

Abstract

Study Objectives: Conflicting reports on prevalence of RLS exist in Asian countries due to differences in sampling strategies and assessment instruments. We assessed the prevalence, correlates, quality of life, and psychiatric comorbidity of RLS in South Korea. Design/setting: Cross-sectional nationwide survey. Participants: Nationally representative sample of 6,509 Korean adults aged 18-64. Measurement & Results: Face-to-face interviews based on the Korean translation of the four features of RLS defined by the International RLS Study Group (IRLSSG), the Korean version of Composite International Diagnostic Interview (K-CIDI), and EuroQol (EQ-5D) were conducted for all participants. The weighted prevalence of RLS in South Korea was 0.9% (men, 0.6%; women, 1.3%). Subjects with RLS had a lower quality of life according to EQ-5D than those without RLS. Adjusted odds ratio for lifetime diagnosis of DSM-IV major depressive disorder (2.57, 95% confidence interval [1.33, 4.96]), panic disorder (18.9 [4.72, 75.9]) and posttraumatic stress disorder (3.76 [1.32, 10.7]) suggest strong association between RLS and DSM-IV depression and anxiety disorders. Conclusions: Prevalence of RLS estimated based on the IRLSSG diagnostic criteria is substantially lower in South Korea than in Western countries. Differences in culture and risk factors that affect the expression of RLS may vary across the countries.

Original languageEnglish (US)
Pages (from-to)1069-1076
Number of pages8
JournalSleep
Volume32
Issue number8
StatePublished - 2009

Fingerprint

Restless Legs Syndrome
Diagnostic and Statistical Manual of Mental Disorders
Republic of Korea
Psychiatry
Quality of Life
Interviews
Panic Disorder
Major Depressive Disorder
Post-Traumatic Stress Disorders
Anxiety Disorders
Comorbidity
Cross-Sectional Studies
Odds Ratio
Confidence Intervals
Depression

Keywords

  • Association
  • Prevalence
  • Psychiatric disorder
  • Quality of life
  • Restless legs syndrome

ASJC Scopus subject areas

  • Physiology (medical)
  • Clinical Neurology

Cite this

Cho, S. J., Hong, J. P., Hahm, B. J., Jeon, H. J., Chang, S. M., Cho, M. J., & Lee, H. B. (2009). Restless legs syndrome in a community sample of Korean adults: Prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders. Sleep, 32(8), 1069-1076.

Restless legs syndrome in a community sample of Korean adults : Prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders. / Cho, Seong Jin; Hong, Jin Pyo; Hahm, Bong Jin; Jeon, Hong Jin; Chang, Sung Man; Cho, Maeng Je; Lee, Hochang B.

In: Sleep, Vol. 32, No. 8, 2009, p. 1069-1076.

Research output: Contribution to journalArticle

Cho, SJ, Hong, JP, Hahm, BJ, Jeon, HJ, Chang, SM, Cho, MJ & Lee, HB 2009, 'Restless legs syndrome in a community sample of Korean adults: Prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders', Sleep, vol. 32, no. 8, pp. 1069-1076.
Cho, Seong Jin ; Hong, Jin Pyo ; Hahm, Bong Jin ; Jeon, Hong Jin ; Chang, Sung Man ; Cho, Maeng Je ; Lee, Hochang B. / Restless legs syndrome in a community sample of Korean adults : Prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders. In: Sleep. 2009 ; Vol. 32, No. 8. pp. 1069-1076.
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abstract = "Study Objectives: Conflicting reports on prevalence of RLS exist in Asian countries due to differences in sampling strategies and assessment instruments. We assessed the prevalence, correlates, quality of life, and psychiatric comorbidity of RLS in South Korea. Design/setting: Cross-sectional nationwide survey. Participants: Nationally representative sample of 6,509 Korean adults aged 18-64. Measurement & Results: Face-to-face interviews based on the Korean translation of the four features of RLS defined by the International RLS Study Group (IRLSSG), the Korean version of Composite International Diagnostic Interview (K-CIDI), and EuroQol (EQ-5D) were conducted for all participants. The weighted prevalence of RLS in South Korea was 0.9{\%} (men, 0.6{\%}; women, 1.3{\%}). Subjects with RLS had a lower quality of life according to EQ-5D than those without RLS. Adjusted odds ratio for lifetime diagnosis of DSM-IV major depressive disorder (2.57, 95{\%} confidence interval [1.33, 4.96]), panic disorder (18.9 [4.72, 75.9]) and posttraumatic stress disorder (3.76 [1.32, 10.7]) suggest strong association between RLS and DSM-IV depression and anxiety disorders. Conclusions: Prevalence of RLS estimated based on the IRLSSG diagnostic criteria is substantially lower in South Korea than in Western countries. Differences in culture and risk factors that affect the expression of RLS may vary across the countries.",
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AB - Study Objectives: Conflicting reports on prevalence of RLS exist in Asian countries due to differences in sampling strategies and assessment instruments. We assessed the prevalence, correlates, quality of life, and psychiatric comorbidity of RLS in South Korea. Design/setting: Cross-sectional nationwide survey. Participants: Nationally representative sample of 6,509 Korean adults aged 18-64. Measurement & Results: Face-to-face interviews based on the Korean translation of the four features of RLS defined by the International RLS Study Group (IRLSSG), the Korean version of Composite International Diagnostic Interview (K-CIDI), and EuroQol (EQ-5D) were conducted for all participants. The weighted prevalence of RLS in South Korea was 0.9% (men, 0.6%; women, 1.3%). Subjects with RLS had a lower quality of life according to EQ-5D than those without RLS. Adjusted odds ratio for lifetime diagnosis of DSM-IV major depressive disorder (2.57, 95% confidence interval [1.33, 4.96]), panic disorder (18.9 [4.72, 75.9]) and posttraumatic stress disorder (3.76 [1.32, 10.7]) suggest strong association between RLS and DSM-IV depression and anxiety disorders. Conclusions: Prevalence of RLS estimated based on the IRLSSG diagnostic criteria is substantially lower in South Korea than in Western countries. Differences in culture and risk factors that affect the expression of RLS may vary across the countries.

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