TY - JOUR
T1 - Responsiveness of the National Eye Institute Refractive Error Quality of Life Instrument to Surgical Correction of Refractive Error
AU - McDonnell, Peter J.
AU - Mangione, Carol
AU - Lee, Paul
AU - Lindblad, Anne S.
AU - Spritzer, Karen L.
AU - Berry, Sandy
AU - Hays, Ron D.
N1 - Funding Information:
Supported by The National Eye Institute, Bethesda, Maryland, and The EMMES Corporation, Rockville, Maryland (contract no.: NO1-EY-6-2112); the American Academy of Ophthalmology; Allergan, Inc.; Bausch & Lomb, Inc.; and others in industry. Ron D. Hays was supported in part by the UCLA/DREW Project EXPORT; National Center on Minority Health & Health Disparities, The National Institutes of Health, Bethesda, Maryland (grant no.: P20-MD00148-01); and the UCLA Center for Health Improvement in Minority Elders/Resource Centers for Minority Aging Research, National Institutes of Health, National Institute of Aging, Bethesda, Maryland (grant no.: AG-02-004).
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2003/12
Y1 - 2003/12
N2 - Objective: Refractive error and the means by which it is corrected may impact substantially on quality of vision and health-related quality of life in ways not captured adequately by standard measures of visual acuity. The goal of this analysis was to evaluate the responsiveness of the National Eye Institute Refractive Error Quality of Life (NEI-RQL) instrument to surgical correction of refractive error. Design: Prospective, multicenter cohort study. Participants: The NEI-RQL, a 42-item measure with 13 scales, was self-administered by 185 patients before and after undergoing surgical correction of myopic or hyperopic refractive error. Preoperative and postoperative clinical information was collected, including refractive error and corrected visual acuity. Methods: Differences between preoperative and postoperative NEI-RQL scores were examined. Responsiveness was assessed using the standardized response mean and the responsiveness statistic. We also compared scales using relative efficiency estimates. Main Outcome Measures: Changes in NEI-RQL scales (clarity of vision, expectations, near vision, far vision, diurnal fluctuations, activity limitations, glare, symptoms, dependence on correction, worry, suboptimal correction, appearance, and satisfaction with correction). Results: For myopes and hyperopes combined, refractive surgical correction was associated with statistically significant (P<0.05) improvements in scores for 11 of 13 scales. The largest improvements, ranging from 26 to 58 points on the 0 to 100 possible score range, were seen in expectations, activity limitations, dependence on correction, appearance, and satisfaction with correction. Separate analysis of myopes and hyperopes revealed similar effects in the 2 groups. Baseline scores were found to be predictive of change after surgery. Conclusions: The NEI-RQL is responsive to changes in vision-targeted health-related quality of life resulting from keratorefractive surgery. This instrument may prove useful for evaluating the beneficial and adverse impacts of surgical and nonsurgical methods of refractive error correction.
AB - Objective: Refractive error and the means by which it is corrected may impact substantially on quality of vision and health-related quality of life in ways not captured adequately by standard measures of visual acuity. The goal of this analysis was to evaluate the responsiveness of the National Eye Institute Refractive Error Quality of Life (NEI-RQL) instrument to surgical correction of refractive error. Design: Prospective, multicenter cohort study. Participants: The NEI-RQL, a 42-item measure with 13 scales, was self-administered by 185 patients before and after undergoing surgical correction of myopic or hyperopic refractive error. Preoperative and postoperative clinical information was collected, including refractive error and corrected visual acuity. Methods: Differences between preoperative and postoperative NEI-RQL scores were examined. Responsiveness was assessed using the standardized response mean and the responsiveness statistic. We also compared scales using relative efficiency estimates. Main Outcome Measures: Changes in NEI-RQL scales (clarity of vision, expectations, near vision, far vision, diurnal fluctuations, activity limitations, glare, symptoms, dependence on correction, worry, suboptimal correction, appearance, and satisfaction with correction). Results: For myopes and hyperopes combined, refractive surgical correction was associated with statistically significant (P<0.05) improvements in scores for 11 of 13 scales. The largest improvements, ranging from 26 to 58 points on the 0 to 100 possible score range, were seen in expectations, activity limitations, dependence on correction, appearance, and satisfaction with correction. Separate analysis of myopes and hyperopes revealed similar effects in the 2 groups. Baseline scores were found to be predictive of change after surgery. Conclusions: The NEI-RQL is responsive to changes in vision-targeted health-related quality of life resulting from keratorefractive surgery. This instrument may prove useful for evaluating the beneficial and adverse impacts of surgical and nonsurgical methods of refractive error correction.
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U2 - 10.1016/j.ophtha.2003.02.004
DO - 10.1016/j.ophtha.2003.02.004
M3 - Article
C2 - 14644711
AN - SCOPUS:0344874646
VL - 110
SP - 2302
EP - 2309
JO - Ophthalmology
JF - Ophthalmology
SN - 0161-6420
IS - 12
ER -