Response to Dr Stephen Cooper's 'On the use of metaphor to understand, explain, or rationalize redundant genes in yeast'

Xuewen Pan; Daniel Yuan; Ping Ye; Joel Bader; Jef D. Boeke

doi:10.1111/j.1567-1364.2008.00357.x

Response to Dr Stephen Cooper's 'On the use of metaphor to understand, explain, or rationalize redundant genes in yeast'

Xuewen Pan, Daniel Yuan, Ping Ye, Joel Bader, Jef D. Boeke

Research output: Contribution to journal › Article › peer-review

Abstract

Earlier use of a metaphor in explaining genetic redundancy in a news article has triggered a commentary and a competing metaphor by Dr Stephen Cooper, who went on to conclude that genetic redundancies are relatively unimportant for microorganisms. We argue here that the new metaphor is flawed and that genetic redundancies are integral to buffering all organisms against environmental and genetic damage.

Original language	English (US)
Pages (from-to)	349-350
Number of pages	2
Journal	FEMS Yeast Research
Volume	8
Issue number	3
DOIs	https://doi.org/10.1111/j.1567-1364.2008.00357.x
State	Published - May 2008

Keywords

DNA repair
DNA replication
Genetic interactions
Saccharomyces cerevisiae
Synthetic lethality

ASJC Scopus subject areas

Microbiology
Applied Microbiology and Biotechnology

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10.1111/j.1567-1364.2008.00357.x

Cite this

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AU - Bader, Joel

AU - Boeke, Jef D.

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KW - Synthetic lethality

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Response to Dr Stephen Cooper's 'On the use of metaphor to understand, explain, or rationalize redundant genes in yeast'

Abstract

Keywords

ASJC Scopus subject areas

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