Respiratory physiologic changes in pregnancy

Robert A. Wise, Albert J. Polito, Vidya Krishnan

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations


In summary, the major physiologic changes that occur in pregnancy are the increased minute ventilation, which is caused by increased respiratory center sensitivity and drive; a compensated respiratory alkalosis; and a low expiratory reserve volume. The vital capacity and measures of forced expiration are well preserved. Patients who have many lung diseases tolerate pregnancy well, with the exception of those who have pulmonary hypertension or chronic respiratory insufficiency from parenchymal or neuromuscular disease.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalImmunology and Allergy Clinics of North America
Issue number1
StatePublished - Feb 2006

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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