Respiratory infections in the U.S. military: Recent experience and control

Jose L. Sanchez, Michael J. Cooper, Christopher A. Myers, James F. Cummings, Kelly G. Vest, Kevin L. Russell, Joyce L. Sanchez, Michelle J. Hiser, Charlotte A. Gaydos

Research output: Contribution to journalArticle

Abstract

This comprehensive review outlines the impact of military-relevant respiratory infections, with special attention to recruit training environments, influenza pandemics in 1918 to 1919 and 2009 to 2010, and peacetime operations and conflicts in the past 25 years. Outbreaks and epidemiologic investigations of viral and bacterial infections among high-risk groups are presented, including (i) experience by recruits at training centers, (ii) impact on advanced trainees in special settings, (iii) morbidity sustained by shipboard personnel at sea, and (iv) experience of deployed personnel. Utilizing a pathogen-by-pathogen approach, we examine (i) epidemiology, (ii) impact in terms of morbidity and operational readiness, (iii) clinical presentation and outbreak potential, (iv) diagnostic modalities, (v) treatment approaches, and (vi) vaccine and other control measures. We also outline military-specific initiatives in (i) surveillance, (ii) vaccine development and policy, (iii) novel influenza and coronavirus diagnostic test development and surveillance methods, (iv) influenza virus transmission and severity prediction modeling efforts, and (v) evaluation and implementation of nonvaccine, nonpharmacologic interventions.

Original languageEnglish (US)
Pages (from-to)743-800
Number of pages58
JournalClinical Microbiology Reviews
Volume28
Issue number3
DOIs
StatePublished - Jan 1 2015

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ASJC Scopus subject areas

  • Epidemiology
  • Immunology and Microbiology(all)
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Sanchez, J. L., Cooper, M. J., Myers, C. A., Cummings, J. F., Vest, K. G., Russell, K. L., Sanchez, J. L., Hiser, M. J., & Gaydos, C. A. (2015). Respiratory infections in the U.S. military: Recent experience and control. Clinical Microbiology Reviews, 28(3), 743-800. https://doi.org/10.1128/CMR.00039-14