TY - JOUR
T1 - Resistance of peripheral and sub-cortical somatosensory pathway to electrical noise
AU - Omrani, Mohsen
AU - Khoshnoodi, Mohammad Ali
AU - Pakarian, Pooya
AU - Abbassian, Abdol Hossein
AU - Shahzadi, Sohrab
PY - 2004/9
Y1 - 2004/9
N2 - The somatosensory system is vulnerable to large amounts of noise distortion. But how does the central nervous system distinguish the peripheral inputs which carry information to the brain from that which does not possess information? To address this question we studied the effect of electrical stimulation of the median nerve on tactile spatial frequency perception in healthy subjects and Parkinson's disease (PD) patients. Subjects were categorized in two groups (healthy and PD patients) and were asked to report if a test tactile frequency pattern (TFP) was the same as the reference TFP given to the other hand. In each case stimulation was either present or absent on the median nerve of the hand holding the test pattern. We observed no impairment of tactile performance in the presence of electrical stimulation of the median nerve. This result together with previous work on direct stimulation of the somatosensory relay nucleus of the thalamus (Abbassian et al., Stereotact Funct Neurosurg 76: 19-28, 2001) in which the same result of no impairment of the tactile discrimination task was observed suggest a high degree of noise tolerance exists in the somatosensory pathway.
AB - The somatosensory system is vulnerable to large amounts of noise distortion. But how does the central nervous system distinguish the peripheral inputs which carry information to the brain from that which does not possess information? To address this question we studied the effect of electrical stimulation of the median nerve on tactile spatial frequency perception in healthy subjects and Parkinson's disease (PD) patients. Subjects were categorized in two groups (healthy and PD patients) and were asked to report if a test tactile frequency pattern (TFP) was the same as the reference TFP given to the other hand. In each case stimulation was either present or absent on the median nerve of the hand holding the test pattern. We observed no impairment of tactile performance in the presence of electrical stimulation of the median nerve. This result together with previous work on direct stimulation of the somatosensory relay nucleus of the thalamus (Abbassian et al., Stereotact Funct Neurosurg 76: 19-28, 2001) in which the same result of no impairment of the tactile discrimination task was observed suggest a high degree of noise tolerance exists in the somatosensory pathway.
KW - Electrical stimulation
KW - Median nerve
KW - Noise resistance
KW - PD
KW - Somatosensory system
KW - Tactile frequency pattern (TFP)
UR - http://www.scopus.com/inward/record.url?scp=11344283581&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=11344283581&partnerID=8YFLogxK
U2 - 10.1080/08990220400012380
DO - 10.1080/08990220400012380
M3 - Article
C2 - 15763900
AN - SCOPUS:11344283581
SN - 0899-0220
VL - 21
SP - 155
EP - 158
JO - Somatosensory and Motor Research
JF - Somatosensory and Motor Research
IS - 3-4
ER -