Research Priorities to Advance the Health and Health Care of Older Adults with Multiple Chronic Conditions

Mayra Tisminetzky, Elizabeth A. Bayliss, Jay S. Magaziner, Heather G. Allore, Kathryn Anzuoni, Cynthia M. Boyd, Thomas M. Gill, Alan S. Go, Susan L. Greenspan, Leah R. Hanson, Mark C. Hornbrook, Dalane W. Kitzman, Eric B. Larson, Mary D. Naylor, Benjamin E. Shirley, Ming Tai-Seale, Linda Teri, Mary E. Tinetti, Heather E. Whitson, Jerry H. Gurwitz

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Objectives: To prioritize research topics relevant to the care of the growing population of older adults with multiple chronic conditions (MCCs). Design: Survey of experts in MCC practice, research, and policy. Topics were derived from white papers, funding announcements, or funded research projects relating to older adults with MCCs. Setting: Survey conducted through the Health Care Systems Research Network (HCSRN) and Claude D. Pepper Older Americans Independence Centers (OAICs) Advancing Geriatrics Infrastructure and Network Growth Initiative, a joint endeavor of the HCSRN and OAICs. Participants: Individuals affiliated with the HCSRN or OAICs and national MCC experts, including individuals affiliated with funding agencies having MCC-related grant portfolios. Measurements: A “top box” methodology was used, counting the number of respondents selecting the top response on a 5-point Likert scale and dividing by the total number of responses to calculate a top box percentage for each of 37 topics. Results: The highest-ranked research topics relevant to the health and healthcare of older adults with MCCs were health-related quality of life in older adults with MCCs; development of assessment tools (to assess, e.g., symptom burden, quality of life, function); interactions between medications, disease processes, and health outcomes; disability; implementation of novel (and scalable) models of care; association between clusters of chronic conditions and clinical, financial, and social outcomes; role of caregivers; symptom burden; shared decision-making to enhance care planning; and tools to improve clinical decision-making. Conclusion: Study findings serve to inform the development of a comprehensive research agenda to address the challenges relating to the care of this “high-need, high-cost” population and the healthcare delivery systems responsible for serving it.

Original languageEnglish (US)
Pages (from-to)1549-1553
Number of pages5
JournalJournal of the American Geriatrics Society
Issue number7
StatePublished - Jul 2017


  • aging
  • geriatrics
  • multimorbidity
  • multiple chronic conditions

ASJC Scopus subject areas

  • Geriatrics and Gerontology


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