Research methods in healthcare epidemiology and antimicrobial stewardship - Quasi-experimental designs

Marin L. Schweizer, Barbara I. Braun, Aaron Milstone

Research output: Contribution to journalArticle

Abstract

Quasi-experimental studies evaluate the association between an intervention and an outcome using experiments in which the intervention is not randomly assigned. Quasi-experimental studies are often used to evaluate rapid responses to outbreaks or other patient safety problems requiring prompt, nonrandomized interventions. Quasi-experimental studies can be categorized into 3 major types: interrupted time-series designs, designs with control groups, and designs without control groups. This methods paper highlights key considerations for quasi-experimental studies in healthcare epidemiology and antimicrobial stewardship, including study design and analytic approaches to avoid selection bias and other common pitfalls of quasi-experimental studies.

Original languageEnglish (US)
Pages (from-to)1135-1140
Number of pages6
JournalInfection Control and Hospital Epidemiology
Volume37
Issue number10
DOIs
StatePublished - Oct 1 2016

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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