Research is defined as "seeking of knowledge, data, or the truth about something". Research in the field of medicine can be divided in "basic science" oriented and "patient oriented" research. The starting point of most research is one or a set of yet unanswered questions. The research question should be formulated precisely and in the field of patient oriented research the answer to the question should be clinically relevant. A research question includes the main occurrence relation, the determinant(s) and the outcome as well as the domain in which the relation will be investigated.
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