Reprogramming somatic cells into pluripotent stem cells using miRNAs

Frederick Anokye-Danso

doi:10.1007/978-1-4939-0512-6_19

Reprogramming somatic cells into pluripotent stem cells using miRNAs

Frederick Anokye-Danso

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Reversal of terminally differentiated somatic cells to ground-state pluripotency has rejuvenated our hopes of generating patient-specific stem cells for therapeutic use in regenerative medicine and drug screening. Originally generated using defined exogenous protein-coding DNA, several methods have been described in reprogramming somatic cells into iPSC. Majority of published methods seek to improve or refine the techniques of reprogramming. This chapter describes reprogramming to pluripotency using miRNAs.

Original language	English (US)
Pages (from-to)	273-281
Number of pages	9
Journal	Methods in Molecular Biology
Volume	1150
DOIs	https://doi.org/10.1007/978-1-4939-0512-6_19
State	Published - 2014
Externally published	Yes

Keywords

Fibroblast
Induced pluripotent stem cells (iPSCs)
Lentivirus
MicroRNAs (miRNAs)
Reprogramming

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-4939-0512-6_19

Cite this

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title = "Reprogramming somatic cells into pluripotent stem cells using miRNAs",

abstract = "Reversal of terminally differentiated somatic cells to ground-state pluripotency has rejuvenated our hopes of generating patient-specific stem cells for therapeutic use in regenerative medicine and drug screening. Originally generated using defined exogenous protein-coding DNA, several methods have been described in reprogramming somatic cells into iPSC. Majority of published methods seek to improve or refine the techniques of reprogramming. This chapter describes reprogramming to pluripotency using miRNAs.",

keywords = "Fibroblast, Induced pluripotent stem cells (iPSCs), Lentivirus, MicroRNAs (miRNAs), Reprogramming",

author = "Frederick Anokye-Danso",

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year = "2014",

doi = "10.1007/978-1-4939-0512-6_19",

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KW - Fibroblast

KW - Induced pluripotent stem cells (iPSCs)

KW - Lentivirus

KW - MicroRNAs (miRNAs)

KW - Reprogramming

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ER -

Reprogramming somatic cells into pluripotent stem cells using miRNAs

Abstract

Keywords

ASJC Scopus subject areas

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