Reprogram to pluripotency: A new logic and a chemical cocktail

Hongjun Song, Guo Li Ming

Research output: Contribution to journalArticlepeer-review


Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.

Original languageEnglish (US)
Pages (from-to)6-7
Number of pages2
JournalNational Science Review
Issue number1
StatePublished - 2014

ASJC Scopus subject areas

  • General


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