Reprogram to pluripotency: A new logic and a chemical cocktail

Hongjun Song, Guo Li Ming

Research output: Contribution to journalArticle

Abstract

Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.

Original languageEnglish (US)
Pages (from-to)6-7
Number of pages2
JournalNational Science Review
Volume1
Issue number1
DOIs
StatePublished - 2014

Fingerprint

Pluripotent Stem Cells
Stem Cell Factor

ASJC Scopus subject areas

  • General

Cite this

Reprogram to pluripotency : A new logic and a chemical cocktail. / Song, Hongjun; Ming, Guo Li.

In: National Science Review, Vol. 1, No. 1, 2014, p. 6-7.

Research output: Contribution to journalArticle

Song, Hongjun ; Ming, Guo Li. / Reprogram to pluripotency : A new logic and a chemical cocktail. In: National Science Review. 2014 ; Vol. 1, No. 1. pp. 6-7.
@article{d52f40e1858240f683a438b0db9d7fa3,
title = "Reprogram to pluripotency: A new logic and a chemical cocktail",
abstract = "Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.",
author = "Hongjun Song and Ming, {Guo Li}",
year = "2014",
doi = "10.1093/nsr/nwt007",
language = "English (US)",
volume = "1",
pages = "6--7",
journal = "National Science Review",
issn = "2053-714X",
publisher = "Oxford University Press",
number = "1",

}

TY - JOUR

T1 - Reprogram to pluripotency

T2 - A new logic and a chemical cocktail

AU - Song, Hongjun

AU - Ming, Guo Li

PY - 2014

Y1 - 2014

N2 - Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.

AB - Somatic cells from animals and humans can be reprogrammed into pluripotent stem cells by pluripotency factors. Hongkui Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage specifiers via balancing competing differentiation forces. In a related study they achieved, for the first time, restoration of pluripotency in adult somatic cells using a chemical cocktail alone.

UR - http://www.scopus.com/inward/record.url?scp=84942522734&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942522734&partnerID=8YFLogxK

U2 - 10.1093/nsr/nwt007

DO - 10.1093/nsr/nwt007

M3 - Article

AN - SCOPUS:84942522734

VL - 1

SP - 6

EP - 7

JO - National Science Review

JF - National Science Review

SN - 2053-714X

IS - 1

ER -