Reproductive impact of MRI-guided focused ultrasound surgery for fibroids: A systematic review of the evidence

Natalie A. Clark, Sunni L. Mumford, James Segars

Research output: Contribution to journalArticle

Abstract

Purpose of review: Magnetic-resonance-guided focused ultrasound surgery (MRgFUS) is a minimally invasive technique for the treatment of uterine fibroids. The purpose of this review is to highlight the impact of MRgFUS on fertility and reproductive outcomes. Recent findings: The role of MRgFUS in the treatment of fibroids has been evolving since its introduction in 2004. Several new devices and techniques including location-specific treatment, volumetric therapy, and vessel-targeted therapy have been introduced over the last few years. Several case series report uncomplicated pregnancy following MRgFUS; however, results of the ongoing studies will further elucidate the utility of MRgFUS in patients planning future fertility. A systematic review of the literature was completed and studies that reported quality of life at baseline and after 6 months were included in a meta-analysis. Summary: MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be the treatment of choice for patients desiring future fertility; however, further investigation is needed.

Original languageEnglish (US)
Pages (from-to)151-161
Number of pages11
JournalCurrent Opinion in Obstetrics and Gynecology
Volume26
Issue number3
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Leiomyoma
Magnetic Resonance Spectroscopy
Fertility
Therapeutics
Quality of Life
Meta-Analysis
Equipment and Supplies
Pregnancy

Keywords

  • fertility
  • fibroids
  • HIFU
  • MRgFUS
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Medicine(all)

Cite this

Reproductive impact of MRI-guided focused ultrasound surgery for fibroids : A systematic review of the evidence. / Clark, Natalie A.; Mumford, Sunni L.; Segars, James.

In: Current Opinion in Obstetrics and Gynecology, Vol. 26, No. 3, 2014, p. 151-161.

Research output: Contribution to journalArticle

@article{9a88839fc84d4234a16291dce09bd2c9,
title = "Reproductive impact of MRI-guided focused ultrasound surgery for fibroids: A systematic review of the evidence",
abstract = "Purpose of review: Magnetic-resonance-guided focused ultrasound surgery (MRgFUS) is a minimally invasive technique for the treatment of uterine fibroids. The purpose of this review is to highlight the impact of MRgFUS on fertility and reproductive outcomes. Recent findings: The role of MRgFUS in the treatment of fibroids has been evolving since its introduction in 2004. Several new devices and techniques including location-specific treatment, volumetric therapy, and vessel-targeted therapy have been introduced over the last few years. Several case series report uncomplicated pregnancy following MRgFUS; however, results of the ongoing studies will further elucidate the utility of MRgFUS in patients planning future fertility. A systematic review of the literature was completed and studies that reported quality of life at baseline and after 6 months were included in a meta-analysis. Summary: MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be the treatment of choice for patients desiring future fertility; however, further investigation is needed.",
keywords = "fertility, fibroids, HIFU, MRgFUS, pregnancy",
author = "Clark, {Natalie A.} and Mumford, {Sunni L.} and James Segars",
year = "2014",
doi = "10.1097/GCO.0000000000000070",
language = "English (US)",
volume = "26",
pages = "151--161",
journal = "Current Opinion in Obstetrics and Gynecology",
issn = "1040-872X",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Reproductive impact of MRI-guided focused ultrasound surgery for fibroids

T2 - A systematic review of the evidence

AU - Clark, Natalie A.

AU - Mumford, Sunni L.

AU - Segars, James

PY - 2014

Y1 - 2014

N2 - Purpose of review: Magnetic-resonance-guided focused ultrasound surgery (MRgFUS) is a minimally invasive technique for the treatment of uterine fibroids. The purpose of this review is to highlight the impact of MRgFUS on fertility and reproductive outcomes. Recent findings: The role of MRgFUS in the treatment of fibroids has been evolving since its introduction in 2004. Several new devices and techniques including location-specific treatment, volumetric therapy, and vessel-targeted therapy have been introduced over the last few years. Several case series report uncomplicated pregnancy following MRgFUS; however, results of the ongoing studies will further elucidate the utility of MRgFUS in patients planning future fertility. A systematic review of the literature was completed and studies that reported quality of life at baseline and after 6 months were included in a meta-analysis. Summary: MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be the treatment of choice for patients desiring future fertility; however, further investigation is needed.

AB - Purpose of review: Magnetic-resonance-guided focused ultrasound surgery (MRgFUS) is a minimally invasive technique for the treatment of uterine fibroids. The purpose of this review is to highlight the impact of MRgFUS on fertility and reproductive outcomes. Recent findings: The role of MRgFUS in the treatment of fibroids has been evolving since its introduction in 2004. Several new devices and techniques including location-specific treatment, volumetric therapy, and vessel-targeted therapy have been introduced over the last few years. Several case series report uncomplicated pregnancy following MRgFUS; however, results of the ongoing studies will further elucidate the utility of MRgFUS in patients planning future fertility. A systematic review of the literature was completed and studies that reported quality of life at baseline and after 6 months were included in a meta-analysis. Summary: MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be the treatment of choice for patients desiring future fertility; however, further investigation is needed.

KW - fertility

KW - fibroids

KW - HIFU

KW - MRgFUS

KW - pregnancy

UR - http://www.scopus.com/inward/record.url?scp=84900459079&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84900459079&partnerID=8YFLogxK

U2 - 10.1097/GCO.0000000000000070

DO - 10.1097/GCO.0000000000000070

M3 - Article

C2 - 24751998

AN - SCOPUS:84900459079

VL - 26

SP - 151

EP - 161

JO - Current Opinion in Obstetrics and Gynecology

JF - Current Opinion in Obstetrics and Gynecology

SN - 1040-872X

IS - 3

ER -