Representation of internal models of action in the autistic brain

Courtney C. Haswell, Jun Izawa, Lauren R Dowell, Stewart H Mostofsky, Reza Shadmehr

Research output: Contribution to journalArticle

Abstract

Children with autism spectrum disorder (ASD) have deficits in motor control, imitation and social function. Does a dysfunction in the neural basis of representing internal models of action contribute to these problems? We measured patterns of generalization as children learned to control a novel tool and found that the autistic brain built a stronger than normal association between self-generated motor commands and proprioceptive feedback; furthermore, the greater the reliance on proprioception, the greater the child's impairments in social function and imitation.

Original languageEnglish (US)
Pages (from-to)970-972
Number of pages3
JournalNature Neuroscience
Volume12
Issue number8
DOIs
StatePublished - Aug 2009

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Brain
Proprioception
Sensory Feedback
Autism Spectrum Disorder

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Representation of internal models of action in the autistic brain. / Haswell, Courtney C.; Izawa, Jun; R Dowell, Lauren; Mostofsky, Stewart H; Shadmehr, Reza.

In: Nature Neuroscience, Vol. 12, No. 8, 08.2009, p. 970-972.

Research output: Contribution to journalArticle

Haswell, Courtney C. ; Izawa, Jun ; R Dowell, Lauren ; Mostofsky, Stewart H ; Shadmehr, Reza. / Representation of internal models of action in the autistic brain. In: Nature Neuroscience. 2009 ; Vol. 12, No. 8. pp. 970-972.
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