Report from the Wellcome Trust/EBA "Perspectives in Clinical Proteomics" retreat - A strategy to implement Next-Generation Proteomic Analyses to the clinic for patient benefit: Pathway to translation

Scott D. Patterson, Jennifer E. Van Eyk, Rosamonde E. Banks

Research output: Contribution to journalArticlepeer-review

Abstract

Proteomics has long been thought to hold the promise of producing results of clinical utility which will influence patient treatment and outcomes. A recent Wellcome Trust/EBI meeting and retreat - "Perspectives in Clinical Proteomics" - brought together experts from a broad range of stakeholder groups with an interest in ensuring proteomics achieves this aim. This viewpoint presents views derived from these forums, proposing a pathway for the development of next-generation proteomic analyses in the clinical setting from selection of candidates through to their validation and ultimate demonstration of utility through health technology assessments. Although not meant to be all encompassing, important elements for proteomics researchers to consider are presented.

Original languageEnglish (US)
Pages (from-to)883-887
Number of pages5
JournalProteomics - Clinical Applications
Volume4
Issue number12
DOIs
StatePublished - Dec 2010

Keywords

  • Biomarker qualification
  • Mass spectrometry
  • Multiple reaction monitoring
  • Selected reaction monitoring

ASJC Scopus subject areas

  • Clinical Biochemistry

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