Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS)

Rabekah Gundry; David Hayden; Paul Boyce; Amy Voltz; Elise Luong; Elizabeth Pugh; Michael Kelley; Rebecca Fan; Joan E. Bailey-Wilson; Dane Witmer; Kimberly Doheny

Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS)

Rabekah Gundry, David Hayden, Paul Boyce, Amy Voltz, Elise Luong, Elizabeth Pugh, Michael Kelley, Rebecca Fan, Joan E. Bailey-Wilson, Dane Witmer, Kimberly Doheny

School of Medicine

Research output: Contribution to conference › Paper › peer-review

Abstract

The utility of MALDI-TOF MS detection of single nucleotide polymorphisms (SNP) was discussed. The study was carried out by genotyped and analyzed 40 SNPs on chromosomes 22 using the Homogeneous Mass EXTEND (hME) assay in one large 4 generation family consisting of 26 individuals. It was observed that, for the chromosome 22 SNP assays analyzed, the assays were originally genotyped up to four times for a single assay. Three mismatched were also found among 1,451 comparisons that equal to 0.21% and the overall missing data after considering all attempts was 3.1%.

Original language	English (US)
Pages	399-401
Number of pages	3
State	Published - 2002
Event	Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002

Other

Other	Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Country/Territory	United States
City	Orlando, FL
Period	6/2/02 → 6/6/02

ASJC Scopus subject areas

Spectroscopy

Cite this

Gundry, R., Hayden, D., Boyce, P., Voltz, A., Luong, E., Pugh, E., Kelley, M., Fan, R., Bailey-Wilson, J. E., Witmer, D., & Doheny, K. (2002). Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS). 399-401. Paper presented at Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, United States.

Gundry, R, Hayden, D, Boyce, P, Voltz, A, Luong, E, Pugh, E, Kelley, M, Fan, R, Bailey-Wilson, JE, Witmer, D & Doheny, K 2002, 'Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS)', Paper presented at Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, United States, 6/2/02 - 6/6/02 pp. 399-401.

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abstract = "The utility of MALDI-TOF MS detection of single nucleotide polymorphisms (SNP) was discussed. The study was carried out by genotyped and analyzed 40 SNPs on chromosomes 22 using the Homogeneous Mass EXTEND (hME) assay in one large 4 generation family consisting of 26 individuals. It was observed that, for the chromosome 22 SNP assays analyzed, the assays were originally genotyped up to four times for a single assay. Three mismatched were also found among 1,451 comparisons that equal to 0.21% and the overall missing data after considering all attempts was 3.1%.",

author = "Rabekah Gundry and David Hayden and Paul Boyce and Amy Voltz and Elise Luong and Elizabeth Pugh and Michael Kelley and Rebecca Fan and Bailey-Wilson, {Joan E.} and Dane Witmer and Kimberly Doheny",

year = "2002",

language = "English (US)",

pages = "399--401",

note = "Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics ; Conference date: 02-06-2002 Through 06-06-2002",

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T1 - Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS)

AU - Gundry, Rabekah

AU - Hayden, David

AU - Boyce, Paul

AU - Voltz, Amy

AU - Luong, Elise

AU - Pugh, Elizabeth

AU - Kelley, Michael

AU - Fan, Rebecca

AU - Bailey-Wilson, Joan E.

AU - Witmer, Dane

AU - Doheny, Kimberly

PY - 2002

Y1 - 2002

N2 - The utility of MALDI-TOF MS detection of single nucleotide polymorphisms (SNP) was discussed. The study was carried out by genotyped and analyzed 40 SNPs on chromosomes 22 using the Homogeneous Mass EXTEND (hME) assay in one large 4 generation family consisting of 26 individuals. It was observed that, for the chromosome 22 SNP assays analyzed, the assays were originally genotyped up to four times for a single assay. Three mismatched were also found among 1,451 comparisons that equal to 0.21% and the overall missing data after considering all attempts was 3.1%.

AB - The utility of MALDI-TOF MS detection of single nucleotide polymorphisms (SNP) was discussed. The study was carried out by genotyped and analyzed 40 SNPs on chromosomes 22 using the Homogeneous Mass EXTEND (hME) assay in one large 4 generation family consisting of 26 individuals. It was observed that, for the chromosome 22 SNP assays analyzed, the assays were originally genotyped up to four times for a single assay. Three mismatched were also found among 1,451 comparisons that equal to 0.21% and the overall missing data after considering all attempts was 3.1%.

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M3 - Paper

AN - SCOPUS:2442645537

SP - 399

EP - 401

T2 - Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics

Y2 - 2 June 2002 through 6 June 2002

ER -

Replication of linkage results using MALDI-TOF detection of single nucleotide polymorphisms (SNPS)

Abstract

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ASJC Scopus subject areas

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