Reperfusion-induced injury manifestations, mechanisms, and clinical relevance

David J. Hearse, Roberto Bolli

Research output: Contribution to journalShort survey

Abstract

Although reperfusion is an absolute prerequisite for the survival of ischemic tissue, it is not necessarily without hazard. Many (but not all) cardiologists are of the opinion that some component of reperfusion may be detrimental and able to inflict injury over and above that attributable to the ischemia. In this article, we define four sequelae of reperfusion that might be designated as "reperfusion injury," we identify possible underlying mechanisms, and we consider whether any of these forms of reperfusion injury are of clinical relevance.

Original languageEnglish (US)
Pages (from-to)233-240
Number of pages8
JournalTrends in Cardiovascular Medicine
Volume1
Issue number6
DOIs
StatePublished - Sep 1991

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Reperfusion-induced injury manifestations, mechanisms, and clinical relevance'. Together they form a unique fingerprint.

  • Cite this