Repeated episodes of neuroleptic-related dyskinesias in autistic children

R. P. Malone, M. Ernst, K. A. Godfrey, J. J. Locascio, M. Campbell

Research output: Contribution to journalArticle

Abstract

The objective of this study was to examine data from 14 autistic children who developed repeated episodes of haloperidol-related dyskinesias in an ongoing, long-term maintenance clinical trial. The sample consisted of 9 males and 5 females, whose ages ranged from 3.4 to 6.7 years. These 14 children are a subsample of 29 children who developed dyskinesias at least once. In each subsequent episode, the dyskinesias tended to occur increasingly earlier and to last longer. Most of the dyskinesias developed upon haloperidol withdrawal. The topography of dyskinesias, the relationship of behavioral symptoms to severity of dyskinesias, and an attempt to characterize subgroups with dyskinesias are also presented.

Original languageEnglish (US)
Pages (from-to)113-117
Number of pages5
JournalPsychopharmacology Bulletin
Volume27
Issue number2
StatePublished - 1991
Externally publishedYes

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Dyskinesias
Antipsychotic Agents
Haloperidol
Behavioral Symptoms
Clinical Trials

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology

Cite this

Malone, R. P., Ernst, M., Godfrey, K. A., Locascio, J. J., & Campbell, M. (1991). Repeated episodes of neuroleptic-related dyskinesias in autistic children. Psychopharmacology Bulletin, 27(2), 113-117.

Repeated episodes of neuroleptic-related dyskinesias in autistic children. / Malone, R. P.; Ernst, M.; Godfrey, K. A.; Locascio, J. J.; Campbell, M.

In: Psychopharmacology Bulletin, Vol. 27, No. 2, 1991, p. 113-117.

Research output: Contribution to journalArticle

Malone, RP, Ernst, M, Godfrey, KA, Locascio, JJ & Campbell, M 1991, 'Repeated episodes of neuroleptic-related dyskinesias in autistic children', Psychopharmacology Bulletin, vol. 27, no. 2, pp. 113-117.
Malone RP, Ernst M, Godfrey KA, Locascio JJ, Campbell M. Repeated episodes of neuroleptic-related dyskinesias in autistic children. Psychopharmacology Bulletin. 1991;27(2):113-117.
Malone, R. P. ; Ernst, M. ; Godfrey, K. A. ; Locascio, J. J. ; Campbell, M. / Repeated episodes of neuroleptic-related dyskinesias in autistic children. In: Psychopharmacology Bulletin. 1991 ; Vol. 27, No. 2. pp. 113-117.
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