Renal transplantation in HIV-positive recipients

Jayme E. Locke, Dorry L. Segev

Research output: Contribution to journalReview articlepeer-review

Abstract

About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among HIV-infected patients. Traditionally, HIV infection has been considered an absolute contraindication to solid-organ transplantation. However, in the context of improved survival, the role for kidney transplantation among HIV-positive patients is currently being revisited. This article discusses long-term outcomes after kidney transplantation in the HAART era and management strategies for the HIV-positive kidney transplant recipient.

Original languageEnglish (US)
Pages (from-to)71-75
Number of pages5
JournalCurrent Infectious Disease Reports
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2010

Keywords

  • Donor selection
  • Human Immunodeficiency Virus (HIV)
  • Immunosuppression
  • Recipient selection
  • Renal transplantation

ASJC Scopus subject areas

  • Infectious Diseases

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