Renal function, erythropoietin, and anemia of older persons

The InCHIANTI study

Alessandro Ble, Jeffrey C. Fink, Richard C. Woodman, Mark A. Klausner, B. Gwen Windham, Jack M. Guralnik, Luigi Ferrucci

Research output: Contribution to journalArticle

Abstract

Background: In the older population, anemia has been associated with poor outcomes including disability and mortality. Understanding the mechanisms leading to anemia is essential to plan better treatment and prevention strategies. We tested the hypothesis that the age-related decline in kidney function is associated with an increased prevalence of anemia and that such an increase is accompanied by a concomitant decrement in erythropoietin levels. Methods: Data were from the InCHIANTI study, a population-based study performed in a sample of community-dwelling older (≥65 years) persons living in Italy. This analysis included 1005 participants with complete data on hemoglobin and erythropoietin levels and markers of renal function. Results: The prevalence of anemia according to the World Health Organization criteria (hemoglobin level 1.50 mL/s) (P

Original languageEnglish (US)
Pages (from-to)2222-2227
Number of pages6
JournalArchives of Internal Medicine
Volume165
Issue number19
DOIs
StatePublished - Oct 24 2005
Externally publishedYes

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Erythropoietin
Anemia
Kidney
Hemoglobins
Independent Living
Italy
Population
Mortality
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Ble, A., Fink, J. C., Woodman, R. C., Klausner, M. A., Windham, B. G., Guralnik, J. M., & Ferrucci, L. (2005). Renal function, erythropoietin, and anemia of older persons: The InCHIANTI study. Archives of Internal Medicine, 165(19), 2222-2227. https://doi.org/10.1001/archinte.165.19.2222

Renal function, erythropoietin, and anemia of older persons : The InCHIANTI study. / Ble, Alessandro; Fink, Jeffrey C.; Woodman, Richard C.; Klausner, Mark A.; Windham, B. Gwen; Guralnik, Jack M.; Ferrucci, Luigi.

In: Archives of Internal Medicine, Vol. 165, No. 19, 24.10.2005, p. 2222-2227.

Research output: Contribution to journalArticle

Ble, A, Fink, JC, Woodman, RC, Klausner, MA, Windham, BG, Guralnik, JM & Ferrucci, L 2005, 'Renal function, erythropoietin, and anemia of older persons: The InCHIANTI study', Archives of Internal Medicine, vol. 165, no. 19, pp. 2222-2227. https://doi.org/10.1001/archinte.165.19.2222
Ble A, Fink JC, Woodman RC, Klausner MA, Windham BG, Guralnik JM et al. Renal function, erythropoietin, and anemia of older persons: The InCHIANTI study. Archives of Internal Medicine. 2005 Oct 24;165(19):2222-2227. https://doi.org/10.1001/archinte.165.19.2222
Ble, Alessandro ; Fink, Jeffrey C. ; Woodman, Richard C. ; Klausner, Mark A. ; Windham, B. Gwen ; Guralnik, Jack M. ; Ferrucci, Luigi. / Renal function, erythropoietin, and anemia of older persons : The InCHIANTI study. In: Archives of Internal Medicine. 2005 ; Vol. 165, No. 19. pp. 2222-2227.
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