Renal cell carcinoma in children, adolescents and young adults: A national cancer database study

Ardavan Akhavan, Morgan Richards, Margarett Shnorhavorian, Adam Goldin, Kenneth Gow, Paul A. Merguerian

Research output: Contribution to journalArticle

Abstract

Purpose We compared the presentation and outcomes of patients younger than 21 years with renal cell carcinoma and determined risk factors associated with mortality. Materials and Methods We searched the National Cancer Database for patients diagnosed with renal cell carcinoma between 1998 and 2011. We evaluated patients younger than 30 years with renal cell carcinoma, including clear cell, chromophobe, papillary and not otherwise specified subcategories. We used logistic regression to compare presenting cancer, demographics and treatment variables in patients 0 to 15 years, 15 to 21 years and 21 to 30 years old. Cox regression analysis was used to determine risk factors for mortality in patients younger than 21. Results Of 3,658 patients younger than 30 years included in the study 161 were younger than 15 and 337 were 15 to 21 years old. A higher proportion of younger patients had renal cell carcinoma not otherwise specified and papillary histology compared to those 21 to 30 years (p

Original languageEnglish (US)
Pages (from-to)1336-1341
Number of pages6
JournalJournal of Urology
Volume193
Issue number4
DOIs
StatePublished - Apr 1 2015

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Renal Cell Carcinoma
Young Adult
Databases
Neoplasms
Mortality
Histology
Logistic Models
Regression Analysis
Demography

Keywords

  • carcinoma
  • kidney neoplasms
  • pediatrics
  • renal cell

ASJC Scopus subject areas

  • Urology
  • Medicine(all)

Cite this

Akhavan, A., Richards, M., Shnorhavorian, M., Goldin, A., Gow, K., & Merguerian, P. A. (2015). Renal cell carcinoma in children, adolescents and young adults: A national cancer database study. Journal of Urology, 193(4), 1336-1341. https://doi.org/10.1016/j.juro.2014.10.108

Renal cell carcinoma in children, adolescents and young adults : A national cancer database study. / Akhavan, Ardavan; Richards, Morgan; Shnorhavorian, Margarett; Goldin, Adam; Gow, Kenneth; Merguerian, Paul A.

In: Journal of Urology, Vol. 193, No. 4, 01.04.2015, p. 1336-1341.

Research output: Contribution to journalArticle

Akhavan, A, Richards, M, Shnorhavorian, M, Goldin, A, Gow, K & Merguerian, PA 2015, 'Renal cell carcinoma in children, adolescents and young adults: A national cancer database study', Journal of Urology, vol. 193, no. 4, pp. 1336-1341. https://doi.org/10.1016/j.juro.2014.10.108
Akhavan A, Richards M, Shnorhavorian M, Goldin A, Gow K, Merguerian PA. Renal cell carcinoma in children, adolescents and young adults: A national cancer database study. Journal of Urology. 2015 Apr 1;193(4):1336-1341. https://doi.org/10.1016/j.juro.2014.10.108
Akhavan, Ardavan ; Richards, Morgan ; Shnorhavorian, Margarett ; Goldin, Adam ; Gow, Kenneth ; Merguerian, Paul A. / Renal cell carcinoma in children, adolescents and young adults : A national cancer database study. In: Journal of Urology. 2015 ; Vol. 193, No. 4. pp. 1336-1341.
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