Remote control of pulmonary blood flow: Initial clinical experience

Antonio F. Corno, Damien Bonnet, Nicole Sekarski, Daniel Sidi, Pascal Vouhé, Ludwig K. Von Segesser, Duke E. Cameron, Renato S. Assad

Research output: Contribution to journalArticle

Abstract

Objective: After positive experimental results were obtained with the FloWatch-R-PAB (EndoArt S.A., Lausanne, Switzerland), an implantable device for pulmonary artery banding with telemetric control, it was tested in a prospective, multicenter clinical trial. Methods: From June to September 2002, 6 patients with a mean age of 10.6 months (1-31 months) and a mean weight of 6. 5 kg (3.5-11 kg) underwent pulmonary artery banding with the implantation of the FloWatch-R-PAB device through median sternotomy (4 patients) or left thoracotomy (2 patients). The diagnoses were the following: univentricular heart (2 patients), complete atrioventricular septal defect (2 patients), ventricular septal defect (1 patient), and multiple ventricular septal defects with double aortic arch (1 patient). The associated procedures were atrioseptostomy with cardiopulmonary bypass (2 patients), closure of patent ductus arteriosus (2 patients), and division of double aortic arch (1 patient). Results: In a mean follow-up of 7 months (6-9 months), there were no early or late deaths, reoperations, or device-related complications. A mean of 5 regulations per patient (range 2-14) were required to adjust the tightening of the pulmonary artery banding, 50% (15/30) within the first postoperative week, 20% (6/30) during the second week, and 30% (9/30) within 8 months after surgery. In 70% (21/30) of the cases, the regulation was required to further narrow the pulmonary artery, and in 30% (9/30) of the cases, the regulation was required to release the pulmonary artery. Conclusions: The initial trial confirmed the adequate functioning of the FloWatch-R-PAB device as telemetrically adjustable pulmonary artery banding. Repeated pulmonary artery banding adjustments, dictated by the clinical need in all patients even weeks after surgery, were accomplished without need for reoperation or invasive procedures. In children requiring pulmonary artery banding, the therapeutic strategies can be expanded by this promising technology. This device should be particularly indicated in patients with transposition of the great arteries requiring left ventricular retraining.

Original languageEnglish (US)
Pages (from-to)1775-1780
Number of pages6
JournalJournal of Thoracic and Cardiovascular Surgery
Volume126
Issue number6
DOIs
StatePublished - Dec 2003
Externally publishedYes

Fingerprint

Lung
Pulmonary Artery
Equipment and Supplies
Ventricular Heart Septal Defects
Thoracic Aorta
Reoperation
Transposition of Great Vessels
Patent Ductus Arteriosus
Sternotomy
Thoracotomy
Cardiopulmonary Bypass
Switzerland
Multicenter Studies
Clinical Trials
Technology
Weights and Measures

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Corno, A. F., Bonnet, D., Sekarski, N., Sidi, D., Vouhé, P., Von Segesser, L. K., ... Assad, R. S. (2003). Remote control of pulmonary blood flow: Initial clinical experience. Journal of Thoracic and Cardiovascular Surgery, 126(6), 1775-1780. https://doi.org/10.1016/j.jtcvs.2003.06.011

Remote control of pulmonary blood flow : Initial clinical experience. / Corno, Antonio F.; Bonnet, Damien; Sekarski, Nicole; Sidi, Daniel; Vouhé, Pascal; Von Segesser, Ludwig K.; Cameron, Duke E.; Assad, Renato S.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 126, No. 6, 12.2003, p. 1775-1780.

Research output: Contribution to journalArticle

Corno, AF, Bonnet, D, Sekarski, N, Sidi, D, Vouhé, P, Von Segesser, LK, Cameron, DE & Assad, RS 2003, 'Remote control of pulmonary blood flow: Initial clinical experience', Journal of Thoracic and Cardiovascular Surgery, vol. 126, no. 6, pp. 1775-1780. https://doi.org/10.1016/j.jtcvs.2003.06.011
Corno AF, Bonnet D, Sekarski N, Sidi D, Vouhé P, Von Segesser LK et al. Remote control of pulmonary blood flow: Initial clinical experience. Journal of Thoracic and Cardiovascular Surgery. 2003 Dec;126(6):1775-1780. https://doi.org/10.1016/j.jtcvs.2003.06.011
Corno, Antonio F. ; Bonnet, Damien ; Sekarski, Nicole ; Sidi, Daniel ; Vouhé, Pascal ; Von Segesser, Ludwig K. ; Cameron, Duke E. ; Assad, Renato S. / Remote control of pulmonary blood flow : Initial clinical experience. In: Journal of Thoracic and Cardiovascular Surgery. 2003 ; Vol. 126, No. 6. pp. 1775-1780.
@article{7af7b49dd3d4453192e8361143a39e0d,
title = "Remote control of pulmonary blood flow: Initial clinical experience",
abstract = "Objective: After positive experimental results were obtained with the FloWatch-R-PAB (EndoArt S.A., Lausanne, Switzerland), an implantable device for pulmonary artery banding with telemetric control, it was tested in a prospective, multicenter clinical trial. Methods: From June to September 2002, 6 patients with a mean age of 10.6 months (1-31 months) and a mean weight of 6. 5 kg (3.5-11 kg) underwent pulmonary artery banding with the implantation of the FloWatch-R-PAB device through median sternotomy (4 patients) or left thoracotomy (2 patients). The diagnoses were the following: univentricular heart (2 patients), complete atrioventricular septal defect (2 patients), ventricular septal defect (1 patient), and multiple ventricular septal defects with double aortic arch (1 patient). The associated procedures were atrioseptostomy with cardiopulmonary bypass (2 patients), closure of patent ductus arteriosus (2 patients), and division of double aortic arch (1 patient). Results: In a mean follow-up of 7 months (6-9 months), there were no early or late deaths, reoperations, or device-related complications. A mean of 5 regulations per patient (range 2-14) were required to adjust the tightening of the pulmonary artery banding, 50{\%} (15/30) within the first postoperative week, 20{\%} (6/30) during the second week, and 30{\%} (9/30) within 8 months after surgery. In 70{\%} (21/30) of the cases, the regulation was required to further narrow the pulmonary artery, and in 30{\%} (9/30) of the cases, the regulation was required to release the pulmonary artery. Conclusions: The initial trial confirmed the adequate functioning of the FloWatch-R-PAB device as telemetrically adjustable pulmonary artery banding. Repeated pulmonary artery banding adjustments, dictated by the clinical need in all patients even weeks after surgery, were accomplished without need for reoperation or invasive procedures. In children requiring pulmonary artery banding, the therapeutic strategies can be expanded by this promising technology. This device should be particularly indicated in patients with transposition of the great arteries requiring left ventricular retraining.",
author = "Corno, {Antonio F.} and Damien Bonnet and Nicole Sekarski and Daniel Sidi and Pascal Vouh{\'e} and {Von Segesser}, {Ludwig K.} and Cameron, {Duke E.} and Assad, {Renato S.}",
year = "2003",
month = "12",
doi = "10.1016/j.jtcvs.2003.06.011",
language = "English (US)",
volume = "126",
pages = "1775--1780",
journal = "Journal of Thoracic and Cardiovascular Surgery",
issn = "0022-5223",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Remote control of pulmonary blood flow

T2 - Initial clinical experience

AU - Corno, Antonio F.

AU - Bonnet, Damien

AU - Sekarski, Nicole

AU - Sidi, Daniel

AU - Vouhé, Pascal

AU - Von Segesser, Ludwig K.

AU - Cameron, Duke E.

AU - Assad, Renato S.

PY - 2003/12

Y1 - 2003/12

N2 - Objective: After positive experimental results were obtained with the FloWatch-R-PAB (EndoArt S.A., Lausanne, Switzerland), an implantable device for pulmonary artery banding with telemetric control, it was tested in a prospective, multicenter clinical trial. Methods: From June to September 2002, 6 patients with a mean age of 10.6 months (1-31 months) and a mean weight of 6. 5 kg (3.5-11 kg) underwent pulmonary artery banding with the implantation of the FloWatch-R-PAB device through median sternotomy (4 patients) or left thoracotomy (2 patients). The diagnoses were the following: univentricular heart (2 patients), complete atrioventricular septal defect (2 patients), ventricular septal defect (1 patient), and multiple ventricular septal defects with double aortic arch (1 patient). The associated procedures were atrioseptostomy with cardiopulmonary bypass (2 patients), closure of patent ductus arteriosus (2 patients), and division of double aortic arch (1 patient). Results: In a mean follow-up of 7 months (6-9 months), there were no early or late deaths, reoperations, or device-related complications. A mean of 5 regulations per patient (range 2-14) were required to adjust the tightening of the pulmonary artery banding, 50% (15/30) within the first postoperative week, 20% (6/30) during the second week, and 30% (9/30) within 8 months after surgery. In 70% (21/30) of the cases, the regulation was required to further narrow the pulmonary artery, and in 30% (9/30) of the cases, the regulation was required to release the pulmonary artery. Conclusions: The initial trial confirmed the adequate functioning of the FloWatch-R-PAB device as telemetrically adjustable pulmonary artery banding. Repeated pulmonary artery banding adjustments, dictated by the clinical need in all patients even weeks after surgery, were accomplished without need for reoperation or invasive procedures. In children requiring pulmonary artery banding, the therapeutic strategies can be expanded by this promising technology. This device should be particularly indicated in patients with transposition of the great arteries requiring left ventricular retraining.

AB - Objective: After positive experimental results were obtained with the FloWatch-R-PAB (EndoArt S.A., Lausanne, Switzerland), an implantable device for pulmonary artery banding with telemetric control, it was tested in a prospective, multicenter clinical trial. Methods: From June to September 2002, 6 patients with a mean age of 10.6 months (1-31 months) and a mean weight of 6. 5 kg (3.5-11 kg) underwent pulmonary artery banding with the implantation of the FloWatch-R-PAB device through median sternotomy (4 patients) or left thoracotomy (2 patients). The diagnoses were the following: univentricular heart (2 patients), complete atrioventricular septal defect (2 patients), ventricular septal defect (1 patient), and multiple ventricular septal defects with double aortic arch (1 patient). The associated procedures were atrioseptostomy with cardiopulmonary bypass (2 patients), closure of patent ductus arteriosus (2 patients), and division of double aortic arch (1 patient). Results: In a mean follow-up of 7 months (6-9 months), there were no early or late deaths, reoperations, or device-related complications. A mean of 5 regulations per patient (range 2-14) were required to adjust the tightening of the pulmonary artery banding, 50% (15/30) within the first postoperative week, 20% (6/30) during the second week, and 30% (9/30) within 8 months after surgery. In 70% (21/30) of the cases, the regulation was required to further narrow the pulmonary artery, and in 30% (9/30) of the cases, the regulation was required to release the pulmonary artery. Conclusions: The initial trial confirmed the adequate functioning of the FloWatch-R-PAB device as telemetrically adjustable pulmonary artery banding. Repeated pulmonary artery banding adjustments, dictated by the clinical need in all patients even weeks after surgery, were accomplished without need for reoperation or invasive procedures. In children requiring pulmonary artery banding, the therapeutic strategies can be expanded by this promising technology. This device should be particularly indicated in patients with transposition of the great arteries requiring left ventricular retraining.

UR - http://www.scopus.com/inward/record.url?scp=0346434097&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0346434097&partnerID=8YFLogxK

U2 - 10.1016/j.jtcvs.2003.06.011

DO - 10.1016/j.jtcvs.2003.06.011

M3 - Article

C2 - 14688686

AN - SCOPUS:0346434097

VL - 126

SP - 1775

EP - 1780

JO - Journal of Thoracic and Cardiovascular Surgery

JF - Journal of Thoracic and Cardiovascular Surgery

SN - 0022-5223

IS - 6

ER -