Remnant-like particle cholesterol levels in patients with dysbetalipoproteinemia or coronary artery disease

Sridevi Devaraj, Gloria Vega, Rick Lange, Scott M. Grundy, Ishwarlal Jialal

Research output: Contribution to journalArticlepeer-review

84 Scopus citations

Abstract

PURPOSE: Several studies have provided support for a proatherogenic role for remnant lipoproteins. Thus, the aim of this study was to compare remnant- like particle (RLP) cholesterol levels in patients with coronary artery disease who were normolipidemic with those in controls of similar age and gender. We also assessed the usefulness of measuring RLP-cholesterol levels in patients with type III dyslipidemia. SUBJECTS AND METHODS: Remnant-like particle cholesterol levels were measured in 63 normolipidemic men with coronary artery disease and 23 male controls of similar age as well as in 15 patients with type III dyslipidemia and 103 controls, using an immunoaffinity method. RESULTS: Remnant-like particle cholesterol levels were significantly increased in men with coronary artery disease compared with controls (7.6 ± 3.8 mg/dL versus 5.7 ± 1.9 mg/dL, P

Original languageEnglish (US)
Pages (from-to)445-450
Number of pages6
JournalAmerican Journal of Medicine
Volume104
Issue number5
DOIs
StatePublished - May 1998
Externally publishedYes

ASJC Scopus subject areas

  • General Nursing

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