Remission and relapse in schizophrenia: The Madras longitudinal study

William W. Eaton, R. Thara, Elizabeth Federman, Allen Tien

Research output: Contribution to journalArticlepeer-review


This paper uses monthly symptom data on 90 first-onset schizophrenics in Madras, India, to characterize, in a continuous manner, the course of remission and relapse. Remission from the first episode occurs in about 6 months and in about 3 months for later episodes. Syndromes from the Present State Exam, assessed at the first episode, predict differentially to early and later parts of the course. Hypomania and simple depression predict early remission from the first episode; flat affect and grandiose delusions predict longer episodes and shorter remissions later in the course.

Original languageEnglish (US)
Pages (from-to)357-363
Number of pages7
JournalJournal of Nervous and Mental Disease
Issue number6
StatePublished - Jun 1998

ASJC Scopus subject areas

  • Psychiatry and Mental health


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