TY - GEN
T1 - Reliability of structural equation modeling of the motor cortex in resting state functional MRI
AU - Kavallappa, T.
AU - Roys, S.
AU - Roy, A.
AU - Greenspan, J.
AU - Gullapalli, R.
AU - McMillan, A.
PY - 2010
Y1 - 2010
N2 - Similar to functional MRI (fMRI), resting-state functional connectivity MRI (rsfcMRI) can be used to measure inter-regional similarities in BOLD fluctuations across the resting brain to yield important information about the connectivity of a functional network, e.g., the motor system. Effective connectivity analysis can be used to evaluate the causal relationships of these networks. In this study, we evaluate the consistency of structural equation modeling (SEM) of resting state motor network involving five regions: the primary motor cortices (LM1, RM1), the supplementary motor area (SMA), and the pre-motor areas (LPMA, RPMA). Overall, our results show that some directional connections within the cortical motor network are consistent, but are not reproducible across the entire study population, and depend on the chosen causal model.
AB - Similar to functional MRI (fMRI), resting-state functional connectivity MRI (rsfcMRI) can be used to measure inter-regional similarities in BOLD fluctuations across the resting brain to yield important information about the connectivity of a functional network, e.g., the motor system. Effective connectivity analysis can be used to evaluate the causal relationships of these networks. In this study, we evaluate the consistency of structural equation modeling (SEM) of resting state motor network involving five regions: the primary motor cortices (LM1, RM1), the supplementary motor area (SMA), and the pre-motor areas (LPMA, RPMA). Overall, our results show that some directional connections within the cortical motor network are consistent, but are not reproducible across the entire study population, and depend on the chosen causal model.
KW - Effective Connectivity
KW - Motor Network
KW - Path Coefficients
KW - Structural Equation Modeling
KW - fMRI
UR - http://www.scopus.com/inward/record.url?scp=78049408342&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78049408342&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-14998-6_123
DO - 10.1007/978-3-642-14998-6_123
M3 - Conference contribution
AN - SCOPUS:78049408342
SN - 9783642149979
T3 - IFMBE Proceedings
SP - 481
EP - 484
BT - 26th Southern Biomedical Engineering Conference SBEC 2010
T2 - 26th Southern Biomedical Engineering Conference, SBEC 2010
Y2 - 30 April 2010 through 2 May 2010
ER -