Release of nuclear DNA template restrictions by specific polyribonucleotides

David G. Brown, Donald S. Coffey

Research output: Contribution to journalArticlepeer-review


Certain synthetic homo-and copolyribonucleotide polymers are capable of releasing the DNA template restriction of isolated nuclei of rat liver cells when assayed with an excess of or in the absence of exogenous DNA polymerase. The purine homopolyribonucleotides are far more effective than are the pyrimidine polymers.

Original languageEnglish (US)
Pages (from-to)176-178
Number of pages3
Issue number3967
StatePublished - 1971
Externally publishedYes

ASJC Scopus subject areas

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