Release of nuclear DNA template restrictions by specific polyribonucleotides

David G. Brown, Donald S. Coffey

Research output: Contribution to journalArticle

Abstract

Certain synthetic homo-and copolyribonucleotide polymers are capable of releasing the DNA template restriction of isolated nuclei of rat liver cells when assayed with an excess of or in the absence of exogenous DNA polymerase. The purine homopolyribonucleotides are far more effective than are the pyrimidine polymers.

Original languageEnglish (US)
Pages (from-to)176-178
Number of pages3
JournalScience
Volume171
Issue number3967
DOIs
StatePublished - Jan 1 1971

ASJC Scopus subject areas

  • General

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