Release of nuclear DNA template restrictions by specific polyribonucleotides

David G. Brown; Donald S. Coffey

doi:10.1126/science.171.3967.176

Release of nuclear DNA template restrictions by specific polyribonucleotides

David G. Brown, Donald S. Coffey

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Certain synthetic homo-and copolyribonucleotide polymers are capable of releasing the DNA template restriction of isolated nuclei of rat liver cells when assayed with an excess of or in the absence of exogenous DNA polymerase. The purine homopolyribonucleotides are far more effective than are the pyrimidine polymers.

Original language	English (US)
Pages (from-to)	176-178
Number of pages	3
Journal	Science
Volume	171
Issue number	3967
DOIs	https://doi.org/10.1126/science.171.3967.176
State	Published - 1971
Externally published	Yes

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title = "Release of nuclear DNA template restrictions by specific polyribonucleotides",

abstract = "Certain synthetic homo-and copolyribonucleotide polymers are capable of releasing the DNA template restriction of isolated nuclei of rat liver cells when assayed with an excess of or in the absence of exogenous DNA polymerase. The purine homopolyribonucleotides are far more effective than are the pyrimidine polymers.",

author = "Brown, {David G.} and Coffey, {Donald S.}",

year = "1971",

doi = "10.1126/science.171.3967.176",

language = "English (US)",

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journal = "Science",

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AU - Brown, David G.

AU - Coffey, Donald S.

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AB - Certain synthetic homo-and copolyribonucleotide polymers are capable of releasing the DNA template restriction of isolated nuclei of rat liver cells when assayed with an excess of or in the absence of exogenous DNA polymerase. The purine homopolyribonucleotides are far more effective than are the pyrimidine polymers.

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JO - Science

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Release of nuclear DNA template restrictions by specific polyribonucleotides

Abstract

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